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Validation of the Framingham general cardiovascular risk score in a multiethnic Asian population: a retrospective cohort study

Overview of attention for article published in BMJ Open, May 2015
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  • Above-average Attention Score compared to outputs of the same age (56th percentile)
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1 policy source

Citations

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173 Mendeley
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Title
Validation of the Framingham general cardiovascular risk score in a multiethnic Asian population: a retrospective cohort study
Published in
BMJ Open, May 2015
DOI 10.1136/bmjopen-2014-007324
Pubmed ID
Authors

Yook Chin Chia, Sarah Yu Weng Gray, Siew Mooi Ching, Hooi Min Lim, Karuthan Chinna

Abstract

This study aims to examine the validity of the Framingham general cardiovascular disease (CVD) risk chart in a primary care setting. This is a 10-year retrospective cohort study. A primary care clinic in a teaching hospital in Malaysia. 967 patients' records were randomly selected from patients who were attending follow-up in the clinic. Baseline demographic data, history of diabetes and smoking, blood pressure (BP), and serum lipids were captured from patient records in 1998. Each patient's Framingham CVD score was computed from these parameters. All atherosclerotic CVD events occurring between 1998 and 2007 were counted. In 1998, mean age was 57 years with 33.8% men, 6.1% smokers, 43.3% diabetics and 59.7% hypertensive. Median BP was 140/80 mm Hg and total cholesterol 6.0 mmol/L (1.3). The predicted median Framingham general CVD risk score for the study population was 21.5% (IQR 1.2-30.0) while the actual CVD events that occurred in the 10 years was 13.1% (127/967). The median CVD points for men was 30.0, giving them a CVD risk of more than 30%; for women it is 18.5, a CVD risk of 21.5%. Our study found that the Framingham general CVD risk score to have moderate discrimination with an area under the receiver operating characteristic curve (AUC) of 0.63. It also discriminates well for Malay (AUC 0.65, p=0.01), Chinese (AUC 0.60, p=0.03), and Indians (AUC 0.65, p=0.001). There was good calibration with Hosmer-Lemeshow test χ(2)=3.25, p=0.78. Taking into account that this cohort of patients were already on treatment, the Framingham General CVD Risk Prediction Score predicts fairly accurately for men and overestimates somewhat for women. In the absence of local risk prediction charts, the Framingham general CVD risk prediction chart is a reasonable alternative for use in a multiethnic group in a primary care setting.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 173 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Malaysia 1 <1%
Unknown 172 99%

Demographic breakdown

Readers by professional status Count As %
Student > Master 29 17%
Student > Bachelor 22 13%
Student > Ph. D. Student 18 10%
Researcher 17 10%
Student > Postgraduate 15 9%
Other 38 22%
Unknown 34 20%
Readers by discipline Count As %
Medicine and Dentistry 71 41%
Nursing and Health Professions 16 9%
Biochemistry, Genetics and Molecular Biology 9 5%
Agricultural and Biological Sciences 8 5%
Pharmacology, Toxicology and Pharmaceutical Science 7 4%
Other 20 12%
Unknown 42 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 March 2021.
All research outputs
#7,459,393
of 22,805,349 outputs
Outputs from BMJ Open
#12,561
of 22,530 outputs
Outputs of similar age
#90,717
of 266,311 outputs
Outputs of similar age from BMJ Open
#185
of 313 outputs
Altmetric has tracked 22,805,349 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 22,530 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 18.2. This one is in the 42nd percentile – i.e., 42% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 266,311 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.
We're also able to compare this research output to 313 others from the same source and published within six weeks on either side of this one. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.