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Reverse transcriptase drug resistance mutations in HIV-1 subtype C infected patients on ART in Karonga District, Malawi

Overview of attention for article published in AIDS Research and Therapy, October 2011
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Title
Reverse transcriptase drug resistance mutations in HIV-1 subtype C infected patients on ART in Karonga District, Malawi
Published in
AIDS Research and Therapy, October 2011
DOI 10.1186/1742-6405-8-38
Pubmed ID
Authors

Vijay B Bansode, Simon AA Travers, Amelia C Crampin, Bagrey Ngwira, Neil French, Judith R Glynn, Grace P McCormack

Abstract

Drug resistance testing before initiation of, or during, antiretroviral therapy (ART) is not routinely performed in resource-limited settings. High levels of viral resistance circulating within the population will have impact on treatment programs by increasing the chances of transmission of resistant strains and treatment failure. Here, we investigate Drug Resistance Mutations (DRMs) from blood samples obtained at regular intervals from patients on ART (Baseline-22 months) in Karonga District, Malawi. One hundred and forty nine reverse transcriptase (RT) consensus sequences were obtained via nested PCR and automated sequencing from blood samples collected at three-month intervals from 75 HIV-1 subtype C infected individuals in the ART programme.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 31 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 8 26%
Other 3 10%
Student > Ph. D. Student 3 10%
Professor 2 6%
Researcher 2 6%
Other 6 19%
Unknown 7 23%
Readers by discipline Count As %
Medicine and Dentistry 13 42%
Immunology and Microbiology 4 13%
Agricultural and Biological Sciences 2 6%
Biochemistry, Genetics and Molecular Biology 2 6%
Arts and Humanities 1 3%
Other 2 6%
Unknown 7 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 November 2011.
All research outputs
#15,236,094
of 22,653,392 outputs
Outputs from AIDS Research and Therapy
#351
of 546 outputs
Outputs of similar age
#94,154
of 135,895 outputs
Outputs of similar age from AIDS Research and Therapy
#4
of 9 outputs
Altmetric has tracked 22,653,392 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 546 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.8. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 135,895 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 5 of them.