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T helper cell mediated-tolerance towards fetal allograft in successful pregnancy

Overview of attention for article published in Clinical and Molecular Allergy, June 2015
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1 tweeter
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Citations

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31 Dimensions

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27 Mendeley
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Title
T helper cell mediated-tolerance towards fetal allograft in successful pregnancy
Published in
Clinical and Molecular Allergy, June 2015
DOI 10.1186/s12948-015-0015-y
Pubmed ID
Authors

Marie-Pierre Piccinni, Letizia Lombardelli, Federica Logiodice, Ornela Kullolli, Sergio Romagnani, Philippe Le Bouteiller

Abstract

Trophoblast HLA-C antigens from paternal origins, which liken the trophoblast to a semiallograft, could be presented by the maternal APCs to the specific maternal CD4+ T helper cells, which could release various cytokines in response to these alloantigens. On the basis of the cytokines produced, these cells can be classified in Th1, Th2 and Th17 cells. Th1 and Th17 cells, known to be responsible for acute allograft rejection, could be involved in miscarriage and Th2 cells together with regulatory CD4+ T cells, known to be involved in allograft tolerance, could be responsible, at least in part, for the success of pregnancy. In this review we focus the role effector CD4+ T cells Th1, Th2 and Th17 cells on the fetal allograft tolerance.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 27 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 22%
Researcher 4 15%
Student > Postgraduate 4 15%
Student > Master 4 15%
Student > Bachelor 2 7%
Other 3 11%
Unknown 4 15%
Readers by discipline Count As %
Medicine and Dentistry 9 33%
Immunology and Microbiology 6 22%
Agricultural and Biological Sciences 2 7%
Biochemistry, Genetics and Molecular Biology 2 7%
Veterinary Science and Veterinary Medicine 2 7%
Other 0 0%
Unknown 6 22%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 June 2015.
All research outputs
#3,672,557
of 5,218,786 outputs
Outputs from Clinical and Molecular Allergy
#54
of 66 outputs
Outputs of similar age
#125,039
of 176,921 outputs
Outputs of similar age from Clinical and Molecular Allergy
#7
of 7 outputs
Altmetric has tracked 5,218,786 research outputs across all sources so far. This one is in the 16th percentile – i.e., 16% of other outputs scored the same or lower than it.
So far Altmetric has tracked 66 research outputs from this source. They receive a mean Attention Score of 3.2. This one is in the 15th percentile – i.e., 15% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 176,921 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one.