Not clear from this work, but are IAPs a rational target for rectal cancer? TNT 🧨 + SMAC mimetic to drive CR and organ preservation higher? Same with esophageal cancer? https://t.co/X7nWrxXqGj
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@pbindler Here's why I think it would help - FG3019 reduces levels of XIAP, which is implicated in resistance https://t.co/1lWOwfIapz $fgen
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High levels of X-linked Inhibitor-of-Apoptosis Protein (XIAP) are indicative of radio chemotherap... http://t.co/ZlOCjhqu24
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High levels of X-linked Inhibitor-of-Apoptosis Protein (XIAP) are indicative of radio chemotherap... http://t.co/ZlOCjhqu24