Title |
Draft genome sequences of three NDM-1-producing Enterobacteriaceae species isolated from Brazil
|
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Published in |
Memórias do Instituto Oswaldo Cruz, May 2015
|
DOI | 10.1590/0074-02760150081 |
Pubmed ID | |
Authors |
Polyana Silva Pereira, Rodolpho Mattos Albano, Marise Dutra Asensi, Ana Paula D’Alincourt Carvalho-Assef |
Abstract |
The emergence of multidrug-resistant Enterobacteriaceae strains producing carbapenemases, such as NDM-1, has become a major public health issue due to a high dissemination capacity and limited treatment options. Here we describe the draft genome of three NDM-1-producing isolates: Providencia rettgeri (CCBH11880), Enterobacter hormaechei subsp. oharae (CCBH10892) and Klebsiella pneumoniae (CCBH13327), isolated in Brazil. Besides blaNDM-1, resistance genes to aminoglycosides [aadA1, aadA2, aac(6')-Ib-cr] and quinolones (qnrA1, qnrB4) were observed which contributed to the multidrug resistance profile. The element ISAba125 was found associated to the blaNDM-1 gene in all strains. |
X Demographics
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Geographical breakdown
Country | Count | As % |
---|---|---|
Brazil | 1 | 33% |
United Kingdom | 1 | 33% |
Unknown | 1 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Brazil | 4 | 8% |
United States | 1 | 2% |
Unknown | 45 | 90% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 8 | 16% |
Student > Master | 8 | 16% |
Student > Bachelor | 7 | 14% |
Student > Doctoral Student | 7 | 14% |
Student > Ph. D. Student | 5 | 10% |
Other | 6 | 12% |
Unknown | 9 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 8 | 16% |
Immunology and Microbiology | 8 | 16% |
Medicine and Dentistry | 8 | 16% |
Agricultural and Biological Sciences | 8 | 16% |
Pharmacology, Toxicology and Pharmaceutical Science | 4 | 8% |
Other | 3 | 6% |
Unknown | 11 | 22% |