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Specific eradication of HIV-1 from infected cultured cells

Overview of attention for article published in AIDS Research and Therapy, January 2010
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#9 of 415)
  • High Attention Score compared to outputs of the same age (94th percentile)
  • High Attention Score compared to outputs of the same age and source (91st percentile)

Mentioned by

twitter
21 tweeters
patent
1 patent
facebook
1 Facebook page

Citations

dimensions_citation
11 Dimensions

Readers on

mendeley
38 Mendeley
citeulike
2 CiteULike
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Title
Specific eradication of HIV-1 from infected cultured cells
Published in
AIDS Research and Therapy, January 2010
DOI 10.1186/1742-6405-7-31
Pubmed ID
Authors

Aviad Levin, Zvi Hayouka, Assaf Friedler, Abraham Loyter

Abstract

A correlation between increase in the integration of Human Immunodeficiency virus-1 (HIV-1) cDNA and cell death was previously established. Here we show that combination of peptides that stimulate integration together with the protease inhibitor Ro 31-8959 caused apoptotic cell death of HIV infected cells with total extermination of the virus. This combination did not have any effect on non-infected cells. Thus it appears that cell death is promoted only in the infected cells. It is our view that the results described in this work suggest a novel approach to specifically promote death of HIV-1 infected cells and thus may eventually be developed into a new and general anti-viral therapy.

Twitter Demographics

The data shown below were collected from the profiles of 21 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 38 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Mozambique 1 3%
Australia 1 3%
Russia 1 3%
Spain 1 3%
United States 1 3%
Unknown 33 87%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 24%
Researcher 9 24%
Student > Master 5 13%
Student > Bachelor 4 11%
Other 3 8%
Other 8 21%
Readers by discipline Count As %
Agricultural and Biological Sciences 17 45%
Medicine and Dentistry 7 18%
Chemistry 4 11%
Biochemistry, Genetics and Molecular Biology 3 8%
Immunology and Microbiology 1 3%
Other 4 11%
Unknown 2 5%

Attention Score in Context

This research output has an Altmetric Attention Score of 21. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 November 2018.
All research outputs
#960,642
of 15,662,006 outputs
Outputs from AIDS Research and Therapy
#9
of 415 outputs
Outputs of similar age
#6,056
of 114,508 outputs
Outputs of similar age from AIDS Research and Therapy
#1
of 12 outputs
Altmetric has tracked 15,662,006 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 415 research outputs from this source. They receive a mean Attention Score of 4.5. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 114,508 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.