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In vitro chemokine (C-C motif) receptor 6-dependent non-inflammatory chemotaxis during spermatogenesis

Overview of attention for article published in Biological Research, May 2018
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Mentioned by

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2 tweeters

Citations

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7 Dimensions

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13 Mendeley
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Title
In vitro chemokine (C-C motif) receptor 6-dependent non-inflammatory chemotaxis during spermatogenesis
Published in
Biological Research, May 2018
DOI 10.1186/s40659-018-0161-z
Pubmed ID
Authors

Ruiying Diao, Xueyong Cai, Lu Liu, Lihua Yang, YongGang Duan, Zhiming Cai, Yaoting Gui, Lisha Mou

Abstract

Chemokine (C-C motif) receptor 6 (CCR6) is present in sperm and plays a significant role in sperm motility and chemotaxis acting in the reproductive tracts. However, the expression and functional significance of CCR6 in testis are still poorly understood, especially in the process of spermatogenesis. CCR6 was expressed in spermatogenic cell lines and its expression was shown in an age-dependent upregulation manner from puberty to adulthood in mouse testis. Immunostaining results confirmed the localization of CCR 6 in testis. Further chemotaxis assays demonstrated that spermatogenic cells GC-1 and -2 exhibited a directional movement toward CCR6-specific ligand such as CCL20 or Sertoli cells in vitro. The present findings indicate that CCR6 is involved in the chemotaxis of spermatogenic cells in vitro and promotes chemotaxis under non-inflammatory conditions during normal spermatogenesis.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 13 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 13 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 2 15%
Researcher 2 15%
Student > Doctoral Student 1 8%
Student > Master 1 8%
Student > Ph. D. Student 1 8%
Other 2 15%
Unknown 4 31%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 5 38%
Medicine and Dentistry 3 23%
Unknown 5 38%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 May 2018.
All research outputs
#8,140,210
of 12,979,316 outputs
Outputs from Biological Research
#165
of 341 outputs
Outputs of similar age
#161,846
of 271,229 outputs
Outputs of similar age from Biological Research
#1
of 1 outputs
Altmetric has tracked 12,979,316 research outputs across all sources so far. This one is in the 23rd percentile – i.e., 23% of other outputs scored the same or lower than it.
So far Altmetric has tracked 341 research outputs from this source. They receive a mean Attention Score of 2.5. This one is in the 37th percentile – i.e., 37% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 271,229 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 30th percentile – i.e., 30% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them