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Orthopaedic regenerative tissue engineering en route to the holy grail: disequilibrium between the demand and the supply in the operating room

Overview of attention for article published in Journal of Experimental Orthopaedics, May 2018
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Title
Orthopaedic regenerative tissue engineering en route to the holy grail: disequilibrium between the demand and the supply in the operating room
Published in
Journal of Experimental Orthopaedics, May 2018
DOI 10.1186/s40634-018-0133-9
Pubmed ID
Authors

Ibrahim Fatih Cengiz, Hélder Pereira, Laura de Girolamo, Magali Cucchiarini, João Espregueira-Mendes, Rui L. Reis, Joaquim Miguel Oliveira

Abstract

Orthopaedic disorders are very frequent, globally found and often partially unresolved despite the substantial advances in science and medicine. Their surgical intervention is multifarious and the most favourable treatment is chosen by the orthopaedic surgeon on a case-by-case basis depending on a number of factors related with the patient and the lesion. Numerous regenerative tissue engineering strategies have been developed and studied extensively in laboratory through in vitro experiments and preclinical in vivo trials with various established animal models, while a small proportion of them reached the operating room. However, based on the available literature, the current strategies have not yet achieved to fully solve the clinical problems. Thus, the gold standards, if existing, remain unchanged in the clinics, notwithstanding the known limitations and drawbacks. Herein, the involvement of regenerative tissue engineering in the clinical orthopaedics is reviewed. The current challenges are indicated and discussed in order to describe the current disequilibrium between the needs and solutions made available in the operating room. Regenerative tissue engineering is a very dynamic field that has a high growth rate and a great openness and ability to incorporate new technologies with passion to edge towards the Holy Grail that is functional tissue regeneration. Thus, the future of clinical solutions making use of regenerative tissue engineering principles for the management of orthopaedic disorders is firmly supported by the clinical need.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 28 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 7 25%
Researcher 5 18%
Student > Ph. D. Student 4 14%
Student > Postgraduate 2 7%
Student > Doctoral Student 2 7%
Other 4 14%
Unknown 4 14%
Readers by discipline Count As %
Medicine and Dentistry 10 36%
Engineering 4 14%
Biochemistry, Genetics and Molecular Biology 3 11%
Environmental Science 1 4%
Materials Science 1 4%
Other 1 4%
Unknown 8 29%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 May 2018.
All research outputs
#11,537,364
of 12,980,672 outputs
Outputs from Journal of Experimental Orthopaedics
#59
of 73 outputs
Outputs of similar age
#235,087
of 271,251 outputs
Outputs of similar age from Journal of Experimental Orthopaedics
#1
of 1 outputs
Altmetric has tracked 12,980,672 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 73 research outputs from this source. They receive a mean Attention Score of 3.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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