Chapter title |
IR Spectroscopic Techniques to Study Isolated Biomolecules
|
---|---|
Chapter number | 621 |
Book title |
Gas-Phase IR Spectroscopy and Structure of Biological Molecules
|
Published in |
Topics in current chemistry, January 2014
|
DOI | 10.1007/128_2014_621 |
Pubmed ID | |
Book ISBNs |
978-3-31-919203-1, 978-3-31-919204-8
|
Authors |
Anouk M. Rijs, Jos Oomens |
Abstract |
The combination of mass spectrometry, infrared action spectroscopy and quantum-chemical calculations provides a variety of approaches to the study of the structure of biologically relevant molecules in vacuo. This chapter reviews some of the experimental methods that are currently in use, which can roughly be divided into two main categories: (1) low-temperature neutral molecules in a molecular beam environment, which can be investigated in a conformationally selective manner by the application of double-resonance laser spectroscopy and (2) ionized species which can conveniently be manipulated and selected by mass spectrometric methods and which can be investigated spectroscopically by wavelength-dependent photo-dissociation. Both approaches rely on the application of infrared tunable laser spectroscopy and the laser sources most commonly used in current studies are briefly reviewed in Sect. 3. Along with quantum-chemical calculations, reviewed in Chap. Gaigeot and Spezia (Top Curr Chem doi:10.1007/128_2014_620, 2014) of this book, the experimental IR spectra reveal a wealth of information on the structural properties of the biological species. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 26 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 7 | 27% |
Researcher | 5 | 19% |
Other | 3 | 12% |
Student > Ph. D. Student | 3 | 12% |
Professor > Associate Professor | 2 | 8% |
Other | 4 | 15% |
Unknown | 2 | 8% |
Readers by discipline | Count | As % |
---|---|---|
Chemistry | 14 | 54% |
Physics and Astronomy | 5 | 19% |
Computer Science | 2 | 8% |
Medicine and Dentistry | 2 | 8% |
Biochemistry, Genetics and Molecular Biology | 1 | 4% |
Other | 0 | 0% |
Unknown | 2 | 8% |