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The subclassification of papillary renal cell carcinoma does not affect oncological outcomes after nephron sparing surgery

Overview of attention for article published in World Journal of Urology, July 2015
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Title
The subclassification of papillary renal cell carcinoma does not affect oncological outcomes after nephron sparing surgery
Published in
World Journal of Urology, July 2015
DOI 10.1007/s00345-015-1634-0
Pubmed ID
Authors

Pierre Bigot, Jean-Christophe Bernhard, Inderbir S. Gill, Nam Son Vuong, Grégory Verhoest, Vincent Flamand, Boris Reix, Evren Suer, Ilker Gökce, Jean Baptiste Beauval, François Xavier Nouhaud, Masatoshi Eto, Eduard Baco, Toru Matsugasumi, Yvonne Chowaniec, Jérôme Rigaud, Claire Lenormand, Christian Pfister, Jean François Hetet, Guillaume Ploussard, Morgan Roupret, Priscilla Léon, Adnan El Bakri, Stéphane Larré, Xavier Tillou, Arnaud Doerfler, Aurélien Descazeaud, Nicolas Koutlidis, Alexandre Schneider, Philippe Sebe, Alexandre Ingels, Abdel Rahmène Azzouzi, Michel Soulié, Arnaud Méjean, Karim Bensalah, Jean-Jacques Patard, the members of the Kidney Cancer group of the CCAFU

Abstract

To evaluate the oncological outcomes of papillary renal cell carcinoma (pRCC) following nephron sparing surgery (NSS) and to determine whether the subclassification type of pRCC could be a prognostic factor for recurrence, progression, and specific death. An international multicentre retrospective study involving 19 institutions and the French network for research on kidney cancer was conducted after IRB approval. We analyzed data of all patients with pRCC who were treated by NSS between 2004 and 2014. We included 486 patients. Tumors were type 1 pRCC in 369 (76 %) cases and type 2 pRCC in 117 (24 %) cases. After a mean follow-up of 35 (1-120) months, 8 (1.6 %) patients experienced a local recurrence, 12 (1.5 %) had a metastatic progression, 24 (4.9 %) died, and 7 (1.4 %) died from cancer. Patients with type I pRCC had more grade II (66.3 vs. 46.1 %; p < 0.001) and less grade III (20 vs. 41 %; p < 0.001) tumors. Three-year estimated cancer-free survival (CFS) rate for type 1 pRCC was 96.5 % and for type 2 pRCC was 95.1 % (p = 0.894), respectively. Three-year estimated cancer-specific survival rate for type 1 pRCC was 98.4 % and for type 2 pRCC was 97.3 % (p = 0.947), respectively. Tumor stage superior to pT1 was the only prognostic factor for CFS (HR 3.5; p = 0.03). Histological subtyping of pRCC has no impact on oncologic outcomes after nephron sparing surgery. In this selected population of pRCC tumors, we found that tumor stage is the only prognostic factor for cancer-free survival.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 33 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 33 100%

Demographic breakdown

Readers by professional status Count As %
Other 4 12%
Student > Bachelor 4 12%
Student > Postgraduate 4 12%
Professor > Associate Professor 4 12%
Student > Ph. D. Student 3 9%
Other 5 15%
Unknown 9 27%
Readers by discipline Count As %
Medicine and Dentistry 17 52%
Nursing and Health Professions 2 6%
Business, Management and Accounting 1 3%
Social Sciences 1 3%
Arts and Humanities 1 3%
Other 0 0%
Unknown 11 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 July 2015.
All research outputs
#15,614,715
of 25,195,876 outputs
Outputs from World Journal of Urology
#1,488
of 2,297 outputs
Outputs of similar age
#136,811
of 268,088 outputs
Outputs of similar age from World Journal of Urology
#19
of 37 outputs
Altmetric has tracked 25,195,876 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,297 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one is in the 34th percentile – i.e., 34% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 268,088 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 37 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 51% of its contemporaries.