Title |
Multi-species bacterial biofilm and intracellular infection in otitis media
|
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Published in |
BMC Pediatrics, October 2011
|
DOI | 10.1186/1471-2431-11-94 |
Pubmed ID | |
Authors |
Ruth B Thornton, Paul J Rigby, Selma P Wiertsema, Pierre Filion, Jennifer Langlands, Harvey L Coates, Shyan Vijayasekaran, Anthony D Keil, Peter C Richmond |
Abstract |
Bacteria which are metabolically active yet unable to be cultured and eradicated by antibiotic treatment are present in the middle ear effusion of children with chronic otitis media with effusion (COME) and recurrent acute otitis media (rAOM). These observations are suggestive of biofilm presence or intracellular sequestration of bacteria and may play a role in OM pathogenesis. The aim of this project is to provide evidence for the presence of otopathogenic bacteria intracellularly or within biofilm in the middle ear mucosa of children with COME or rAOM. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 4 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 4 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Russia | 1 | <1% |
Denmark | 1 | <1% |
Unknown | 102 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 18 | 17% |
Researcher | 18 | 17% |
Student > Master | 15 | 14% |
Other | 8 | 8% |
Student > Bachelor | 7 | 7% |
Other | 17 | 16% |
Unknown | 21 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 26 | 25% |
Agricultural and Biological Sciences | 20 | 19% |
Immunology and Microbiology | 11 | 11% |
Biochemistry, Genetics and Molecular Biology | 7 | 7% |
Engineering | 5 | 5% |
Other | 9 | 9% |
Unknown | 26 | 25% |