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Exosomes in cancer: small particle, big player

Overview of attention for article published in Journal of Hematology & Oncology, July 2015
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (61st percentile)

Mentioned by

twitter
4 tweeters
facebook
1 Facebook page

Citations

dimensions_citation
290 Dimensions

Readers on

mendeley
494 Mendeley
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Title
Exosomes in cancer: small particle, big player
Published in
Journal of Hematology & Oncology, July 2015
DOI 10.1186/s13045-015-0181-x
Pubmed ID
Authors

Xu Zhang, Xiao Yuan, Hui Shi, Lijun Wu, Hui Qian, Wenrong Xu

Abstract

Exosomes have emerged as a novel mode of intercellular communication. Exosomes can shuttle bioactive molecules including proteins, DNA, mRNA, as well as non-coding RNAs from one cell to another, leading to the exchange of genetic information and reprogramming of the recipient cells. Increasing evidence suggests that tumor cells release excessive amount of exosomes, which may influence tumor initiation, growth, progression, metastasis, and drug resistance. In addition, exosomes transfer message from tumor cells to immune cells and stromal cells, contributing to the escape from immune surveillance and the formation of tumor niche. In this review, we highlight the recent advances in the biology of exosomes as cancer communicasomes. We review the multifaceted roles of exosomes, the small secreted particles, in communicating with other cells within tumor microenvironment. Given that exosomes are cell type specific, stable, and accessible from body fluids, exosomes may provide promising biomarkers for cancer diagnosis and represent new targets for cancer therapy.

Twitter Demographics

The data shown below were collected from the profiles of 4 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 494 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 <1%
Denmark 3 <1%
Brazil 2 <1%
Argentina 1 <1%
Canada 1 <1%
United Kingdom 1 <1%
China 1 <1%
Japan 1 <1%
Belgium 1 <1%
Other 0 0%
Unknown 480 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 131 27%
Student > Master 85 17%
Researcher 69 14%
Student > Bachelor 66 13%
Student > Doctoral Student 36 7%
Other 67 14%
Unknown 40 8%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 156 32%
Agricultural and Biological Sciences 113 23%
Medicine and Dentistry 60 12%
Engineering 25 5%
Immunology and Microbiology 20 4%
Other 61 12%
Unknown 59 12%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 May 2018.
All research outputs
#6,874,799
of 12,959,714 outputs
Outputs from Journal of Hematology & Oncology
#218
of 573 outputs
Outputs of similar age
#86,063
of 230,036 outputs
Outputs of similar age from Journal of Hematology & Oncology
#1
of 1 outputs
Altmetric has tracked 12,959,714 research outputs across all sources so far. This one is in the 46th percentile – i.e., 46% of other outputs scored the same or lower than it.
So far Altmetric has tracked 573 research outputs from this source. They receive a mean Attention Score of 3.5. This one has gotten more attention than average, scoring higher than 61% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 230,036 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them