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Direct transcriptional reprogramming to nephron progenitors

Overview of attention for article published in Current Opinion in Genetics & Development, July 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (77th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (55th percentile)

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1 X user
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2 patents

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24 Mendeley
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1 CiteULike
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Title
Direct transcriptional reprogramming to nephron progenitors
Published in
Current Opinion in Genetics & Development, July 2015
DOI 10.1016/j.gde.2015.06.001
Pubmed ID
Authors

Jessica M Vanslambrouck, Melissa H Little

Abstract

The direct reprogramming of one cell fate to another represents an attractive option for the generation of specific endpoints for cellular therapy. This appears to require both the reactivation of critical transcription factor regulatory networks and chromatin remodelling. The direct reprogramming of mature renal epithelial cell lines to a nephron progenitor state has been reported. However, our limited knowledge of the optimal growth conditions to maintain this state remains a challenge for their therapeutic application. Here we examine whether nephron progenitors as an endpoint of direct reprogramming have been suitably defined and whether alternative options for reprogramming to kidney exist.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 24 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 25%
Researcher 4 17%
Student > Bachelor 3 13%
Student > Doctoral Student 2 8%
Professor 2 8%
Other 3 13%
Unknown 4 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 6 25%
Biochemistry, Genetics and Molecular Biology 6 25%
Medicine and Dentistry 5 21%
Arts and Humanities 1 4%
Engineering 1 4%
Other 0 0%
Unknown 5 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 November 2022.
All research outputs
#5,338,695
of 25,373,627 outputs
Outputs from Current Opinion in Genetics & Development
#476
of 1,740 outputs
Outputs of similar age
#61,706
of 276,503 outputs
Outputs of similar age from Current Opinion in Genetics & Development
#8
of 18 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done well and is in the 78th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,740 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one has gotten more attention than average, scoring higher than 72% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 276,503 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 77% of its contemporaries.
We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 55% of its contemporaries.