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The potential for prevention of dementia across two decades: the prospective, population-based Rotterdam Study

Overview of attention for article published in BMC Medicine, July 2015
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (96th percentile)

Mentioned by

news
3 news outlets
blogs
1 blog
policy
1 policy source
twitter
30 tweeters
facebook
1 Facebook page

Citations

dimensions_citation
140 Dimensions

Readers on

mendeley
166 Mendeley
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Title
The potential for prevention of dementia across two decades: the prospective, population-based Rotterdam Study
Published in
BMC Medicine, July 2015
DOI 10.1186/s12916-015-0377-5
Pubmed ID
Authors

Renée FAG de Bruijn, Michiel J Bos, Marileen LP Portegies, Albert Hofman, Oscar H Franco, Peter J Koudstaal, M Arfan Ikram

Abstract

Cardiovascular factors and low education are important risk factors of dementia. We provide contemporary estimates of the proportion of dementia cases that could be prevented if modifiable risk factors were eliminated, i.e., population attributable risk (PAR). Furthermore, we studied whether the PAR has changed across the last two decades. We included 7,003 participants of the original cohort (starting in 1990) and 2,953 participants of the extended cohort (starting in 2000) of the Rotterdam Study. Both cohorts were followed for dementia until ten years after baseline. We calculated the PAR of overweight, hypertension, diabetes mellitus, cholesterol, smoking, and education. Additionally, we assessed the PAR of stroke, coronary heart disease, heart failure, and atrial fibrillation. We calculated the PAR for each risk factor separately and the combined PAR taking into account the interaction of risk factors. During 57,996 person-years, 624 participants of the original cohort developed dementia, and during 26,177 person-years, 145 participants of the extended cohort developed dementia. The combined PAR in the original cohort was 0.23 (95 % CI, 0.05-0.62). The PAR in the extended cohort was slightly higher at 0.30 (95 % CI, 0.06-0.76). The combined PAR including cardiovascular diseases was 0.25 (95 % CI, 0.07-0.62) in the original cohort and 0.33 (95 % CI, 0.07-0.77) in the extended cohort. A substantial part of dementia cases could be prevented if modifiable risk factors would be eliminated. Although prevention and treatment options of cardiovascular risk factors and diseases have improved, the preventive potential for dementia has not declined over the last two decades.

Twitter Demographics

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Mendeley readers

The data shown below were compiled from readership statistics for 166 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 3 2%
Unknown 163 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 29 17%
Researcher 26 16%
Student > Master 25 15%
Student > Bachelor 22 13%
Student > Postgraduate 11 7%
Other 34 20%
Unknown 19 11%
Readers by discipline Count As %
Medicine and Dentistry 52 31%
Neuroscience 25 15%
Nursing and Health Professions 10 6%
Biochemistry, Genetics and Molecular Biology 9 5%
Agricultural and Biological Sciences 8 5%
Other 26 16%
Unknown 36 22%

Attention Score in Context

This research output has an Altmetric Attention Score of 51. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 September 2017.
All research outputs
#450,584
of 16,109,844 outputs
Outputs from BMC Medicine
#364
of 2,517 outputs
Outputs of similar age
#7,843
of 237,056 outputs
Outputs of similar age from BMC Medicine
#1
of 1 outputs
Altmetric has tracked 16,109,844 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,517 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 37.5. This one has done well, scoring higher than 85% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 237,056 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them