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The role of magnetic resonance imaging in the evaluation of transfusional iron overload in myelodysplastic syndromes

Overview of attention for article published in Revista Brasileira de Hematologia e Hemoterapia, July 2015
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  • Among the highest-scoring outputs from this source (#29 of 174)
  • Average Attention Score compared to outputs of the same age
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3 tweeters

Citations

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4 Dimensions

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36 Mendeley
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Title
The role of magnetic resonance imaging in the evaluation of transfusional iron overload in myelodysplastic syndromes
Published in
Revista Brasileira de Hematologia e Hemoterapia, July 2015
DOI 10.1016/j.bjhh.2015.03.014
Pubmed ID
Authors

Emmanouil Petrou, Sophie Mavrogeni, Vasiliki Karali, Genovefa Kolovou, Marie-Christine Kyrtsonis, Petros P. Sfikakis, Panayiotis Panayiotidis

Abstract

Myelodysplastic syndromes represent a group of heterogeneous hematopoietic neoplasms derived from an abnormal multipotent progenitor cell, characterized by a hyperproliferative bone marrow, dysplasia of the cellular hemopoietic elements and ineffective erythropoiesis. Anemia is a common finding in myelodysplastic syndrome patients, and blood transfusions are the only therapeutic option in approximately 40% of cases. The most serious side effect of regular blood transfusion is iron overload. Currently, cardiovascular magnetic resonance using T2 is routinely used to identify patients with myocardial iron overload and to guide chelation therapy, tailored to prevent iron toxicity in the heart. This is a major validated non-invasive measure of myocardial iron overloading and is superior to surrogates such as serum ferritin, liver iron, ventricular ejection fraction and tissue Doppler parameters. The indication for iron chelation therapy in myelodysplastic syndrome patients is currently controversial. However, cardiovascular magnetic resonance may offer an excellent non-invasive, diagnostic tool for iron overload assessment in myelodysplastic syndromes. Further studies are needed to establish the precise indications of chelation therapy and the clinical implications of this treatment on survival in myelodysplastic syndromes.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 36 100%

Demographic breakdown

Readers by professional status Count As %
Other 5 14%
Student > Bachelor 5 14%
Student > Ph. D. Student 4 11%
Researcher 4 11%
Student > Master 2 6%
Other 4 11%
Unknown 12 33%
Readers by discipline Count As %
Medicine and Dentistry 16 44%
Biochemistry, Genetics and Molecular Biology 4 11%
Business, Management and Accounting 1 3%
Immunology and Microbiology 1 3%
Computer Science 1 3%
Other 0 0%
Unknown 13 36%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 August 2015.
All research outputs
#2,746,457
of 5,526,446 outputs
Outputs from Revista Brasileira de Hematologia e Hemoterapia
#29
of 174 outputs
Outputs of similar age
#96,512
of 193,372 outputs
Outputs of similar age from Revista Brasileira de Hematologia e Hemoterapia
#4
of 10 outputs
Altmetric has tracked 5,526,446 research outputs across all sources so far. This one is in the 47th percentile – i.e., 47% of other outputs scored the same or lower than it.
So far Altmetric has tracked 174 research outputs from this source. They receive a mean Attention Score of 1.0. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 193,372 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 6 of them.