Title |
Efficacy of a proprietary formulation of fipronil/(S)-methoprene/cyphenothrin against Ixodes scapularis tick infestations on dogs
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Published in |
Parasites & Vectors, July 2015
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DOI | 10.1186/s13071-015-0992-1 |
Pubmed ID | |
Authors |
Doug Carithers, William Russell Everett, Sheila J. Gross, Ruchika Solanki |
Abstract |
Efficacy of FRONTLINE® TRITAK® For Dogs (fipronil/(S)-methoprene/cyphenothrin, Merial, Inc., Duluth, GA) against Ixodes scapularis was evaluated in two separate, but concurrent laboratory studies. One day after topical treatment with placebo or active, dogs (n = 24) were infested with 50 unfed adult Ixodes scapularis ticks, with repeat infestations on Days 7, 14, 21 and 28. The number of live ticks was counted at 6 hours post-infestation in the first study (n = 12) and at 24 hours post-infestation in the second study (n = 12). Observed efficacies in study 1 were 93-99 % at 6 hour assessments on Day 1 through Day 28 and in the second study, 98-100 % at 24 hour assessments, occurring on Day 2 through Day 29. A single dose of FRONTLINE® TRITAK® For Dogs (fipronil/(S)-methoprene/cyphenothrin) (0.67 ml or 1.34 ml) prevented the establishment of a new infestation following treatment, as well as the repeated weekly re-infestations with Ixodes scapularis ticks, for 4 weeks. |
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Unknown | 1 | 100% |
Demographic breakdown
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
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Unknown | 8 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 3 | 38% |
Student > Bachelor | 1 | 13% |
Student > Doctoral Student | 1 | 13% |
Student > Ph. D. Student | 1 | 13% |
Researcher | 1 | 13% |
Other | 0 | 0% |
Unknown | 1 | 13% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 3 | 38% |
Veterinary Science and Veterinary Medicine | 2 | 25% |
Nursing and Health Professions | 1 | 13% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 13% |
Unknown | 1 | 13% |