Title |
Noncoding RNAs and chronic inflammation: Micro‐managing the fire within
|
---|---|
Published in |
BioEssays, August 2015
|
DOI | 10.1002/bies.201500054 |
Pubmed ID | |
Authors |
Margaret Alexander, Ryan M. O'Connell |
Abstract |
Inflammatory responses are essential for the clearance of pathogens and the repair of injured tissues; however, if these responses are not properly controlled chronic inflammation can occur. Chronic inflammation is now recognized as a contributing factor to many age-associated diseases including metabolic disorders, arthritis, neurodegeneration, and cardiovascular disease. Due to the connection between chronic inflammation and these diseases, it is essential to understand underlying mechanisms behind this process. In this review, factors that contribute to chronic inflammation are discussed. Further, we emphasize the emerging roles of microRNAs (miRNAs) and other noncoding RNAs (ncRNA) in regulating chronic inflammatory states, making them important future diagnostic markers and therapeutic targets. Copyright Line: © 2015 The Authors BioEssays Published by Wiley-VCH Verlag GmbH & Co. KGaA. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
India | 1 | 11% |
United Kingdom | 1 | 11% |
Switzerland | 1 | 11% |
France | 1 | 11% |
Unknown | 5 | 56% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 6 | 67% |
Scientists | 3 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 2% |
Unknown | 58 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 13 | 22% |
Researcher | 12 | 20% |
Student > Bachelor | 8 | 14% |
Student > Doctoral Student | 4 | 7% |
Professor > Associate Professor | 4 | 7% |
Other | 6 | 10% |
Unknown | 12 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 13 | 22% |
Medicine and Dentistry | 9 | 15% |
Biochemistry, Genetics and Molecular Biology | 8 | 14% |
Neuroscience | 5 | 8% |
Immunology and Microbiology | 3 | 5% |
Other | 8 | 14% |
Unknown | 13 | 22% |