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MicroRNAs, cancer and ionizing radiation: Where are we?

Overview of attention for article published in Revista da Associação Médica Brasileira, June 2015
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1 tweeter

Citations

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20 Dimensions

Readers on

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28 Mendeley
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Title
MicroRNAs, cancer and ionizing radiation: Where are we?
Published in
Revista da Associação Médica Brasileira, June 2015
DOI 10.1590/1806-9282.61.03.275
Pubmed ID
Authors

Gustavo Nader Marta, Bernardo Garicochea, André Lopes Carvalho, Juliana M. Real, Luiz Paulo Kowalski

Abstract

The aim of this study is to describe the biogenesis of microRNA, its relations with carcinogenesis, and the correlation between microRNA and ionizing radiation (IR), focusing on radioresponsiveness. It is known that microRNA biogenesis is well established and involves different enzymatic cleavages, resulting in the production of mature microRNA. MicroRNAs are involved in carcinogenesis. Their interaction is related to the genetic and epigenetic changes associated with activation of proto-oncogenes or inactivation of tumor suppressor genes. Several studies have shown that the levels of expression of some microRNAs vary significantly after irradiation. There are evidences that microRNAs can influence cellular response after IR. In addition, microRNAs are related to modulation of the expression of several post-transcriptional targets in DNA damage response pathways, and to the DNA damage repair regulation mechanism. Future studies can clarify a possible clinical use of microRNAs as a new class of radiosensitive agents.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 1 4%
Unknown 27 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 29%
Student > Master 6 21%
Researcher 5 18%
Student > Doctoral Student 2 7%
Other 1 4%
Other 0 0%
Unknown 6 21%
Readers by discipline Count As %
Agricultural and Biological Sciences 10 36%
Biochemistry, Genetics and Molecular Biology 6 21%
Medicine and Dentistry 3 11%
Environmental Science 1 4%
Arts and Humanities 1 4%
Other 0 0%
Unknown 7 25%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 August 2015.
All research outputs
#11,192,331
of 12,577,171 outputs
Outputs from Revista da Associação Médica Brasileira
#327
of 452 outputs
Outputs of similar age
#193,378
of 234,354 outputs
Outputs of similar age from Revista da Associação Médica Brasileira
#7
of 7 outputs
Altmetric has tracked 12,577,171 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 452 research outputs from this source. They receive a mean Attention Score of 2.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 234,354 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one.