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X Demographics
Mendeley readers
| Title |
RELATIONSHIP BETWEEN ZINCEMIA, SUPEROXIDE DISMUTASE ACTIVITY AND MARKER OF OXIDATIVE STRESS IN WOMEN WITH BREAST CANCER.
|
|---|---|
| Published in |
Nutrición Hospitalaria, August 2015
|
| DOI | 10.3305/nh.2015.32.2.9204 |
| Pubmed ID | |
| Authors |
Camila Guedes Borges de Araújo, Aldenora Oliveira do Nascimento Holanda, Cinthya Vivianne de Souza Rocha, Ayla Patricia Soares do Nascimento, Camila Maria Simplício Revoredo, Benedito Borges da Silva, Nadir do Nascimento Nogueira, Dilina do Nascimento Marreiro |
| Abstract |
studies show changes in zinc metabolism in women with breast cancer. This mineral has antioxidant action, and disorders in its biochemical parameters are related to poor prognosis of the disease and increase in the carcinogenic process. this study evaluated the activity of enzyme superoxide dismutase and biochemical parameters related to zinc, and investigated the existence of correlation between these variables and the marker of oxidative stress in these patients. this was a case-control study with 66 women aged between 20 and 50 years old, distributed into: case group (women with breast cancer, n = 34) and control group (healthy women, n = 32). Zinc intake was analyzed by three-day food diary, using Nutwin software, version 1.5. Plasma and erythrocyte zinc concentrations were determined by flame atomic absorption spectrophotometry method (λ = 213.9). Superoxide dismutase activity was assessed by Griess colorimetric method, and plasma thiobarbituric acid reactive substances (TBARS) were analyzed. mean levels of zinc intake, superoxide dismutase and TBARS were higher than recommended for the study participants with statistical difference for enzyme superoxide dismutase (p < 0.05). Mean plasma and erythrocyte concentrations of zinc were reduced in both groups (p > 0.05). therefore, it can be assumed that zinc intake in women with breast cancer does not impact plasma and erythrocyte concentrations of this mineral. High superoxide dismutase activity in women with breast cancer may be due to a compensatory mechanism of regulation via oxidative stress found in this disease. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 16 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 16 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Doctoral Student | 5 | 31% |
| Student > Master | 4 | 25% |
| Student > Bachelor | 3 | 19% |
| Researcher | 2 | 13% |
| Student > Postgraduate | 1 | 6% |
| Other | 0 | 0% |
| Unknown | 1 | 6% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 5 | 31% |
| Agricultural and Biological Sciences | 3 | 19% |
| Psychology | 2 | 13% |
| Biochemistry, Genetics and Molecular Biology | 1 | 6% |
| Immunology and Microbiology | 1 | 6% |
| Other | 3 | 19% |
| Unknown | 1 | 6% |