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Metabolic Activity and mRNA Levels of Human Cardiac CYP450s Involved in Drug Metabolism

Overview of attention for article published in PLOS ONE, December 2010
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1 research highlight platform

Citations

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63 Dimensions

Readers on

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44 Mendeley
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1 CiteULike
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Title
Metabolic Activity and mRNA Levels of Human Cardiac CYP450s Involved in Drug Metabolism
Published in
PLOS ONE, December 2010
DOI 10.1371/journal.pone.0015666
Pubmed ID
Authors

Veronique Michaud, Martin Frappier, Marie-Christine Dumas, Jacques Turgeon

Abstract

Tissue-specific expression of CYP450s can regulate the intracellular concentration of drugs and explain inter-subject variability in drug action. The overall objective of our study was to determine in a large cohort of samples, mRNA levels and CYP450 activity expressed in the human heart.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Canada 1 2%
Unknown 43 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 11 25%
Student > Ph. D. Student 7 16%
Student > Bachelor 5 11%
Other 3 7%
Professor 3 7%
Other 8 18%
Unknown 7 16%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 11 25%
Medicine and Dentistry 10 23%
Agricultural and Biological Sciences 9 20%
Biochemistry, Genetics and Molecular Biology 3 7%
Decision Sciences 1 2%
Other 1 2%
Unknown 9 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 October 2011.
All research outputs
#15,238,442
of 22,656,971 outputs
Outputs from PLOS ONE
#129,737
of 193,432 outputs
Outputs of similar age
#140,410
of 180,379 outputs
Outputs of similar age from PLOS ONE
#809
of 1,022 outputs
Altmetric has tracked 22,656,971 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 193,432 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one is in the 24th percentile – i.e., 24% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 180,379 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1,022 others from the same source and published within six weeks on either side of this one. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.