Title |
Proposal for diagnostic criteria for IgG4-related kidney disease
|
---|---|
Published in |
Clinical and Experimental Nephrology, October 2011
|
DOI | 10.1007/s10157-011-0521-2 |
Pubmed ID | |
Authors |
Mitsuhiro Kawano, Takako Saeki, Hitoshi Nakashima, Shinichi Nishi, Yutaka Yamaguchi, Satoshi Hisano, Nobuaki Yamanaka, Dai Inoue, Motohisa Yamamoto, Hiroki Takahashi, Hideki Nomura, Takashi Taguchi, Hisanori Umehara, Hirofumi Makino, Takao Saito |
Abstract |
IgG4-related disease has attracted wide attention recently. It is characterized by a high level of serum IgG4 and dense infiltration of IgG4-positive plasma cells into multiple organs, with the kidney being one representative target. Although several sets of diagnostic criteria for autoimmune pancreatitis (AIP) are available and renal lesion is recognized as an extra-pancreatic manifestation of AIP, it is difficult to differentiate IgG4-related tubulointerstitial nephritis (TIN) without AIP from other types of TIN. To clarify the entity of IgG4-related kidney disease (IgG4-RKD) and support in-depth studies, the Japanese Society of Nephrology has established a working group to prepare diagnostic criteria for IgG4-RKD. |
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