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The opioid epidemic: a central role for the blood brain barrier in opioid analgesia and abuse

Overview of attention for article published in Fluids and Barriers of the CNS, November 2017
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#4 of 365)
  • High Attention Score compared to outputs of the same age (94th percentile)
  • High Attention Score compared to outputs of the same age and source (85th percentile)

Mentioned by

news
5 news outlets
twitter
1 X user

Citations

dimensions_citation
61 Dimensions

Readers on

mendeley
133 Mendeley
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Title
The opioid epidemic: a central role for the blood brain barrier in opioid analgesia and abuse
Published in
Fluids and Barriers of the CNS, November 2017
DOI 10.1186/s12987-017-0080-3
Pubmed ID
Authors

Charles P. Schaefer, Margaret E. Tome, Thomas P. Davis

Abstract

Opioids are currently the primary treatment method used to manage both acute and chronic pain. In the past two to three decades, there has been a surge in the use, abuse and misuse of opioids. The mechanism by which opioids relieve pain and induce euphoria is dependent on the drug crossing the blood-brain barrier and accessing the central nervous system. This suggests the blood brain barrier plays a central role in both the benefits and risks of opioid use. The complex physiological responses to opioids that provide the benefits and drive the abuse also needs to be considered in the resolution of the opioid epidemic.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 133 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 133 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 37 28%
Student > Ph. D. Student 15 11%
Other 10 8%
Student > Master 9 7%
Student > Doctoral Student 8 6%
Other 18 14%
Unknown 36 27%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 18 14%
Medicine and Dentistry 12 9%
Neuroscience 12 9%
Biochemistry, Genetics and Molecular Biology 11 8%
Nursing and Health Professions 7 5%
Other 28 21%
Unknown 45 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 39. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 January 2022.
All research outputs
#884,431
of 22,888,307 outputs
Outputs from Fluids and Barriers of the CNS
#4
of 365 outputs
Outputs of similar age
#22,176
of 437,545 outputs
Outputs of similar age from Fluids and Barriers of the CNS
#1
of 7 outputs
Altmetric has tracked 22,888,307 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 365 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.2. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 437,545 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them