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The opioid epidemic: a central role for the blood brain barrier in opioid analgesia and abuse

Overview of attention for article published in Fluids and Barriers of the CNS, November 2017
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#1 of 154)
  • High Attention Score compared to outputs of the same age (93rd percentile)

Mentioned by

news
5 news outlets

Citations

dimensions_citation
9 Dimensions

Readers on

mendeley
48 Mendeley
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Title
The opioid epidemic: a central role for the blood brain barrier in opioid analgesia and abuse
Published in
Fluids and Barriers of the CNS, November 2017
DOI 10.1186/s12987-017-0080-3
Pubmed ID
Authors

Charles P. Schaefer, Margaret E. Tome, Thomas P. Davis

Abstract

Opioids are currently the primary treatment method used to manage both acute and chronic pain. In the past two to three decades, there has been a surge in the use, abuse and misuse of opioids. The mechanism by which opioids relieve pain and induce euphoria is dependent on the drug crossing the blood-brain barrier and accessing the central nervous system. This suggests the blood brain barrier plays a central role in both the benefits and risks of opioid use. The complex physiological responses to opioids that provide the benefits and drive the abuse also needs to be considered in the resolution of the opioid epidemic.

Mendeley readers

The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 48 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 12 25%
Unspecified 9 19%
Other 8 17%
Student > Ph. D. Student 6 13%
Student > Doctoral Student 5 10%
Other 8 17%
Readers by discipline Count As %
Unspecified 12 25%
Pharmacology, Toxicology and Pharmaceutical Science 7 15%
Medicine and Dentistry 7 15%
Neuroscience 6 13%
Biochemistry, Genetics and Molecular Biology 3 6%
Other 13 27%

Attention Score in Context

This research output has an Altmetric Attention Score of 36. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 February 2019.
All research outputs
#459,303
of 13,415,438 outputs
Outputs from Fluids and Barriers of the CNS
#1
of 154 outputs
Outputs of similar age
#18,167
of 268,409 outputs
Outputs of similar age from Fluids and Barriers of the CNS
#1
of 1 outputs
Altmetric has tracked 13,415,438 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 154 research outputs from this source. They receive a mean Attention Score of 3.7. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 268,409 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them