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Reconstructing A/B compartments as revealed by Hi-C using long-range correlations in epigenetic data

Overview of attention for article published in Genome Biology, August 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (91st percentile)
  • Above-average Attention Score compared to outputs of the same age and source (59th percentile)

Mentioned by

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31 X users
wikipedia
1 Wikipedia page
googleplus
1 Google+ user

Citations

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250 Dimensions

Readers on

mendeley
470 Mendeley
citeulike
2 CiteULike
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Title
Reconstructing A/B compartments as revealed by Hi-C using long-range correlations in epigenetic data
Published in
Genome Biology, August 2015
DOI 10.1186/s13059-015-0741-y
Pubmed ID
Authors

Jean-Philippe Fortin, Kasper D. Hansen

Abstract

Analysis of Hi-C data has shown that the genome can be divided into twocompartments called A/B compartments. These compartments are cell-type specific and are associated with open and closed chromatin. We show that A/B compartments can reliably be estimated using epigenetic data from several different platforms: the Illumina 450k DNA methylation microarray, DNase hypersensitivity sequencing, single-cell ATAC sequencing and single-cell whole-genome bisulfite sequencing. We do this by exploiting that the structure of long-range correlations differs between open and closed compartments. This work makes A/B compartment assignment readily available in a wide variety of cell types, including many human cancers.

X Demographics

X Demographics

The data shown below were collected from the profiles of 31 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 470 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 3 <1%
United States 3 <1%
Denmark 2 <1%
United Kingdom 2 <1%
Lithuania 1 <1%
Canada 1 <1%
Korea, Republic of 1 <1%
China 1 <1%
Sweden 1 <1%
Other 2 <1%
Unknown 453 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 121 26%
Researcher 96 20%
Student > Bachelor 44 9%
Student > Master 38 8%
Student > Doctoral Student 25 5%
Other 53 11%
Unknown 93 20%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 149 32%
Agricultural and Biological Sciences 139 30%
Computer Science 28 6%
Medicine and Dentistry 13 3%
Physics and Astronomy 10 2%
Other 31 7%
Unknown 100 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 22. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 May 2021.
All research outputs
#1,759,500
of 25,658,139 outputs
Outputs from Genome Biology
#1,451
of 4,498 outputs
Outputs of similar age
#22,766
of 280,151 outputs
Outputs of similar age from Genome Biology
#34
of 83 outputs
Altmetric has tracked 25,658,139 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,498 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.5. This one has gotten more attention than average, scoring higher than 67% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,151 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 83 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 59% of its contemporaries.