Inhibitors of the Ras-Raf-MEK-Erk pathway are effective against cancers, and may be useful for some neurological diseases, but most do not cross the blood-brain barrier. Many drugs for brain cancers have failed clinical trials due to poor BBB crossing. ht
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Great review by #cbtddc member Kathy Warren. Join Kathy and 60 other researchers and clinical academics working to #beatbraincancer by joining our #collaborativeresearchdatabase - https://t.co/DhNXCS8ZDg @pinkbools @DannisVV @JGreenGroup @rumanrahman01 @D
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#pedcns #dipg Beyond the Blood:Brain Barrier: The Importance of Central Nervous System (CNS) Pharmacokinetics for the Treatment of CNS Tumors, Including Diffuse Intrinsic Pontine Glioma. https://t.co/Sse1O1El4K
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Beyond the Blood:Brain Barrier: The Importance of Central Nervous System (CNS) Pharmacokinetics for the Treatment of CNS Tumors, Including Diffuse Intrinsic Pontine Glioma. https://t.co/RqAhnUq1Vz