Title |
Clinical and laboratorial features of oral candidiasis in HIV-positive patients
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Published in |
Revista da Sociedade Brasileira de Medicina Tropical, June 2018
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DOI | 10.1590/0037-8682-0241-2017 |
Pubmed ID | |
Authors |
Regiane Nogueira Spalanzani, Karine Mattos, Luiza Inahe Marques, Pedro Fernando Diniz Barros, Pamela Iruama Peres Pereira, Anamaria Mello Miranda Paniago, Rinaldo Poncio Mendes, Marilene Rodrigues Chang |
Abstract |
We describe the clinical and laboratorial features of oral candidiasis in 66 HIV-positive patients. Polymerase chain reaction-based techniques were performed for differentiation of Candida spp. isolated from patients at a public teaching hospital in Midwest Brazil. Oral lesions, mainly pseudomembranous, were significantly related to higher levels of immunosuppression. Of 45 Candida isolates, 66.7% were C. albicans. Most of the isolates were susceptible to the antifungal drugs tested. Oral lesions were associated with higher immunosuppression levels. Lower susceptibility to antifungals by non-albicans isolates supports the importance of surveillance studies using susceptibility tests to aid in the treatment. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 75 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 17 | 23% |
Student > Postgraduate | 10 | 13% |
Student > Master | 5 | 7% |
Researcher | 4 | 5% |
Other | 3 | 4% |
Other | 10 | 13% |
Unknown | 26 | 35% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 22 | 29% |
Immunology and Microbiology | 7 | 9% |
Pharmacology, Toxicology and Pharmaceutical Science | 4 | 5% |
Biochemistry, Genetics and Molecular Biology | 2 | 3% |
Unspecified | 2 | 3% |
Other | 12 | 16% |
Unknown | 26 | 35% |