Title |
The Salford Lung Study protocol: a pragmatic, randomised phase III real-world effectiveness trial in chronic obstructive pulmonary disease
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Published in |
Respiratory Research, September 2015
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DOI | 10.1186/s12931-015-0267-6 |
Pubmed ID | |
Authors |
Nawar Diar Bakerly, Ashley Woodcock, John P. New, J. Martin Gibson, Wei Wu, David Leather, Jørgen Vestbo |
Abstract |
New treatments need to be evaluated in real-world clinical practice to account for co-morbidities, adherence and polypharmacy. Patients with chronic obstructive pulmonary disease (COPD), ≥40 years old, with exacerbation in the previous 3 years are randomised 1:1 to once-daily fluticasone furoate 100 μg/vilanterol 25 μg in a novel dry-powder inhaler versus continuing their existing therapy. The primary endpoint is the mean annual rate of COPD exacerbations; an electronic medical record allows real-time collection and monitoring of endpoint and safety data. The Salford Lung Study is the world's first pragmatic randomised controlled trial of a pre-licensed medication in COPD. Clinicaltrials.gov identifier NCT01551758 . |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 3 | 43% |
Venezuela, Bolivarian Republic of | 1 | 14% |
Unknown | 3 | 43% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 6 | 86% |
Practitioners (doctors, other healthcare professionals) | 1 | 14% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | 1% |
Korea, Republic of | 1 | 1% |
United States | 1 | 1% |
Unknown | 93 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 19 | 20% |
Other | 16 | 17% |
Student > Master | 15 | 16% |
Student > Ph. D. Student | 7 | 7% |
Student > Bachelor | 6 | 6% |
Other | 9 | 9% |
Unknown | 24 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 30 | 31% |
Pharmacology, Toxicology and Pharmaceutical Science | 10 | 10% |
Nursing and Health Professions | 10 | 10% |
Computer Science | 4 | 4% |
Agricultural and Biological Sciences | 4 | 4% |
Other | 11 | 11% |
Unknown | 27 | 28% |