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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Persistence of Aβ seeds in APP null mouse brain
|
|---|---|
| Published in |
Nature Neuroscience, September 2015
|
| DOI | 10.1038/nn.4117 |
| Pubmed ID | |
| Authors |
Lan Ye, Sarah K Fritschi, Juliane Schelle, Ulrike Obermüller, Karoline Degenhardt, Stephan A Kaeser, Yvonne S Eisele, Lary C Walker, Frank Baumann, Matthias Staufenbiel, Mathias Jucker |
| Abstract |
Cerebral β-amyloidosis is induced by inoculation of Aβ seeds into APP transgenic mice, but not into App(-/-) (APP null) mice. We found that brain extracts from APP null mice that had been inoculated with Aβ seeds up to 6 months previously still induced β-amyloidosis in APP transgenic hosts following secondary transmission. Thus, Aβ seeds can persist in the brain for months, and they regain propagative and pathogenic activity in the presence of host Aβ. |
X Demographics
The data shown below were collected from the profiles of 23 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 6 | 26% |
| United States | 4 | 17% |
| Canada | 2 | 9% |
| Spain | 1 | 4% |
| Portugal | 1 | 4% |
| Brazil | 1 | 4% |
| France | 1 | 4% |
| Unknown | 7 | 30% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 16 | 70% |
| Scientists | 6 | 26% |
| Science communicators (journalists, bloggers, editors) | 1 | 4% |
Mendeley readers
The data shown below were compiled from readership statistics for 166 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 3 | 2% |
| Germany | 3 | 2% |
| France | 2 | 1% |
| United Kingdom | 2 | 1% |
| Unknown | 156 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 43 | 26% |
| Researcher | 36 | 22% |
| Student > Master | 16 | 10% |
| Student > Bachelor | 14 | 8% |
| Professor | 11 | 7% |
| Other | 24 | 14% |
| Unknown | 22 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 43 | 26% |
| Agricultural and Biological Sciences | 41 | 25% |
| Biochemistry, Genetics and Molecular Biology | 16 | 10% |
| Medicine and Dentistry | 16 | 10% |
| Chemistry | 4 | 2% |
| Other | 13 | 8% |
| Unknown | 33 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 72. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 December 2023.
All research outputs
#604,730
of 25,837,817 outputs
Outputs from Nature Neuroscience
#1,105
of 5,702 outputs
Outputs of similar age
#7,985
of 282,365 outputs
Outputs of similar age from Nature Neuroscience
#25
of 74 outputs
Altmetric has tracked 25,837,817 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,702 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 57.9. This one has done well, scoring higher than 80% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 282,365 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 74 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.