↓ Skip to main content

Does dexamethasone act in neuropeptides SP and CGRP in neurogenic inflammation of the skin? An experimental study.

Overview of attention for article published in Acta Cirurgica Brasileira, August 2015
Altmetric Badge

About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (54th percentile)

Mentioned by

twitter
2 tweeters

Citations

dimensions_citation
2 Dimensions

Readers on

mendeley
15 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Does dexamethasone act in neuropeptides SP and CGRP in neurogenic inflammation of the skin? An experimental study.
Published in
Acta Cirurgica Brasileira, August 2015
DOI 10.1590/s0102-865020150080000002
Pubmed ID
Authors

Freitas, Jose Octavio Gonçalves de, Quieregatto, Paulo Rogério, Hochman, Bernardo, Lapin, Guilherme Abbud Franco, Mella, Stella Maria Botequio, Maximino, Jessica Ruivo, Chadi, Gerson, Ferreira, Lydia Masako

Abstract

To investigate the neuropeptides substance P (SP) and calcitonin gene-related peptide (CGRP) after subcutaneous injection of dexamethasone prior to skin incision in rats. Twenty seven Wistar-EPM-1 rats were randomly divided into three groups. The sham group (SG) of rats was injected with 0.9 % saline. The second group (Dexa) was injected with 1.0 mg/kg dexamethasone, and the third group (Dexa+) was injected with 10.0 mg/kg dexamethasone. In all groups, the three subcutaneous injections were performed 30 minutes prior to the surgical skin incision and tissue collection. SP and CGRP (15 kDa pro-CGRP and 5 kDa CGRP) were quantified by Western Blotting. No statistically significant differences (p>0.05) were found in pro-CGRP, CGRP and SP values in all three groups. The anti-inflammatory effect of dexamethasone did not occur when the substance P and calcitonin gene-related peptide levels were altered during the neurogenic inflammation process of skin wound healing in rats.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 15 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 20%
Student > Bachelor 2 13%
Student > Master 2 13%
Student > Ph. D. Student 1 7%
Other 1 7%
Other 0 0%
Unknown 6 40%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 3 20%
Agricultural and Biological Sciences 1 7%
Nursing and Health Professions 1 7%
Pharmacology, Toxicology and Pharmaceutical Science 1 7%
Computer Science 1 7%
Other 2 13%
Unknown 6 40%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 January 2016.
All research outputs
#3,038,377
of 7,003,089 outputs
Outputs from Acta Cirurgica Brasileira
#12
of 86 outputs
Outputs of similar age
#95,340
of 225,473 outputs
Outputs of similar age from Acta Cirurgica Brasileira
#1
of 2 outputs
Altmetric has tracked 7,003,089 research outputs across all sources so far. This one has received more attention than most of these and is in the 54th percentile.
So far Altmetric has tracked 86 research outputs from this source. They receive a mean Attention Score of 1.0. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 225,473 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 54% of its contemporaries.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them