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X Demographics
Mendeley readers
Attention Score in Context
| Title |
From Gene Targeting to Genome Editing: Transgenic animals applications and beyond
|
|---|---|
| Published in |
Anais da Academia Brasileira de Ciências, August 2015
|
| DOI | 10.1590/0001-3765201520140710 |
| Pubmed ID | |
| Authors |
MAURÍCIO ROCHA-MARTINS, GABRIEL R. CAVALHEIRO, GABRIEL E. MATOS-RODRIGUES, RODRIGO A.P. MARTINS |
| Abstract |
Genome modification technologies are powerful tools for molecular biology and related areas. Advances in animal transgenesis and genome editing technologies during the past three decades allowed systematic interrogation of gene function that can help model how the genome influences cellular physiology. Genetic engineering via homologous recombination (HR) has been the standard method to modify genomic sequences. Nevertheless, nuclease-guided genome editing methods that were developed recently, such as ZFN, TALEN and CRISPR/Cas, opened new perspectives for biomedical research. Here, we present a brief historical perspective of genome modification methods, focusing on transgenic mice models. Moreover, we describe how new techniques were discovered and improved, present the paradigm shifts and discuss their limitations and applications for biomedical research as well as possible future directions. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Indonesia | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 172 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Denmark | 1 | <1% |
| Unknown | 171 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 49 | 28% |
| Student > Master | 24 | 14% |
| Student > Ph. D. Student | 22 | 13% |
| Researcher | 15 | 9% |
| Student > Doctoral Student | 7 | 4% |
| Other | 20 | 12% |
| Unknown | 35 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 54 | 31% |
| Agricultural and Biological Sciences | 42 | 24% |
| Immunology and Microbiology | 6 | 3% |
| Neuroscience | 6 | 3% |
| Medicine and Dentistry | 5 | 3% |
| Other | 21 | 12% |
| Unknown | 38 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 April 2023.
All research outputs
#4,734,111
of 25,986,827 outputs
Outputs from Anais da Academia Brasileira de Ciências
#3
of 3 outputs
Outputs of similar age
#53,585
of 277,646 outputs
Outputs of similar age from Anais da Academia Brasileira de Ciências
#1
of 2 outputs
Altmetric has tracked 25,986,827 research outputs across all sources so far. Compared to these this one has done well and is in the 81st percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3 research outputs from this source. They receive a mean Attention Score of 3.8. This one scored the same or higher as 0 of them.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 277,646 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them