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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The potential for immunoglobulins and host defense peptides (HDPs) to reduce the use of antibiotics in animal production
|
|---|---|
| Published in |
Veterinary Research, July 2018
|
| DOI | 10.1186/s13567-018-0558-2 |
| Pubmed ID | |
| Authors |
Albert van Dijk, Chris J. Hedegaard, Henk P. Haagsman, Peter M. H. Heegaard |
| Abstract |
Innate defense mechanisms are aimed at quickly containing and removing infectious microorganisms and involve local stromal and immune cell activation, neutrophil recruitment and activation and the induction of host defense peptides (defensins and cathelicidins), acute phase proteins and complement activation. As an alternative to antibiotics, innate immune mechanisms are highly relevant as they offer rapid general ways to, at least partially, protect against infections and enable the build-up of a sufficient adaptive immune response. This review describes two classes of promising alternatives to antibiotics based on components of the innate host defense. First we describe immunoglobulins applied to mimic the way in which they work in the newborn as locally acting broadly active defense molecules enforcing innate immunity barriers. Secondly, the potential of host defense peptides with different modes of action, used directly, induced in situ or used as vaccine adjuvants is described. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 81 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 81 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 13 | 16% |
| Student > Bachelor | 11 | 14% |
| Researcher | 9 | 11% |
| Student > Ph. D. Student | 7 | 9% |
| Student > Doctoral Student | 4 | 5% |
| Other | 9 | 11% |
| Unknown | 28 | 35% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 13 | 16% |
| Agricultural and Biological Sciences | 12 | 15% |
| Veterinary Science and Veterinary Medicine | 8 | 10% |
| Immunology and Microbiology | 8 | 10% |
| Medicine and Dentistry | 3 | 4% |
| Other | 6 | 7% |
| Unknown | 31 | 38% |
Attention Score in Context
This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 August 2018.
All research outputs
#4,721,995
of 25,385,509 outputs
Outputs from Veterinary Research
#202
of 1,337 outputs
Outputs of similar age
#83,686
of 340,738 outputs
Outputs of similar age from Veterinary Research
#8
of 37 outputs
Altmetric has tracked 25,385,509 research outputs across all sources so far. Compared to these this one has done well and is in the 81st percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,337 research outputs from this source. They receive a mean Attention Score of 5.0. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 340,738 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 75% of its contemporaries.
We're also able to compare this research output to 37 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 78% of its contemporaries.