Title |
AluScan: a method for genome-wide scanning of sequence and structure variations in the human genome
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Published in |
BMC Genomics, November 2011
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DOI | 10.1186/1471-2164-12-564 |
Pubmed ID | |
Authors |
Lingling Mei, Xiaofan Ding, Shui-Ying Tsang, Frank W Pun, Siu-Kin Ng, Jianfeng Yang, Cunyou Zhao, Dezhi Li, Weiqing Wan, Chi-Hung Yu, Tze-Ching Tan, Wai-Sang Poon, Gilberto Ka-Kit Leung, Ho-Keung Ng, Liwei Zhang, Hong Xue |
Abstract |
To complement next-generation sequencing technologies, there is a pressing need for efficient pre-sequencing capture methods with reduced costs and DNA requirement. The Alu family of short interspersed nucleotide elements is the most abundant type of transposable elements in the human genome and a recognized source of genome instability. With over one million Alu elements distributed throughout the genome, they are well positioned to facilitate genome-wide sequence amplification and capture of regions likely to harbor genetic variation hotspots of biological relevance. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 4% |
Spain | 1 | 2% |
Sweden | 1 | 2% |
Russia | 1 | 2% |
Unknown | 47 | 90% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 18 | 35% |
Student > Ph. D. Student | 7 | 13% |
Student > Master | 6 | 12% |
Student > Bachelor | 3 | 6% |
Other | 3 | 6% |
Other | 7 | 13% |
Unknown | 8 | 15% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 23 | 44% |
Biochemistry, Genetics and Molecular Biology | 8 | 15% |
Computer Science | 4 | 8% |
Medicine and Dentistry | 3 | 6% |
Economics, Econometrics and Finance | 1 | 2% |
Other | 3 | 6% |
Unknown | 10 | 19% |