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A review on hepatocyte nuclear factor-1beta and tumor

Overview of attention for article published in Cell & Bioscience, October 2015
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About this Attention Score

  • Among the highest-scoring outputs from this source (#37 of 161)
  • Above-average Attention Score compared to outputs of the same age (59th percentile)
  • Good Attention Score compared to outputs of the same age and source (72nd percentile)

Mentioned by

twitter
4 tweeters

Citations

dimensions_citation
14 Dimensions

Readers on

mendeley
21 Mendeley
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Title
A review on hepatocyte nuclear factor-1beta and tumor
Published in
Cell & Bioscience, October 2015
DOI 10.1186/s13578-015-0049-3
Pubmed ID
Authors

Dan-Dan Yu, Shi-Wei Guo, Ying-Ying Jing, Yu-Long Dong, Li-Xin Wei

Abstract

Hepatocyte nuclear factor-1beta (HNF1β) was initially identified as a liver-specific transcription factor. It is a homeobox transcription factor that functions as a homodimer or heterodimer with HNF1α. HNF1β plays an important role in organogenesis during embryonic stage, especially of the liver, kidney, and pancreas. Mutations in the HNF1β gene cause maturity-onset diabetes of the young type 5 (MODY5), renal cysts, genital malformations, and pancreas atrophy. Recently, it has been shown that the expression of HNF1β is associated with cancer risk in several tumors, including hepatocellular carcinoma, pancreatic carcinoma, renal cancer, ovarian cancer, endometrial cancer, and prostate cancer. HNF1β also regulates the expression of genes associated with stem/progenitor cells, which indicates that HNF1β may play an important role in stem cell regulation. In this review, we discuss some of the current developments about HNF1β and tumor, the relationship between HNF1β and stem/progenitor cells, and the potential pathogenesis of HNF1β in various tumors.

Twitter Demographics

The data shown below were collected from the profiles of 4 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 21 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 6 29%
Student > Ph. D. Student 4 19%
Researcher 3 14%
Student > Doctoral Student 2 10%
Student > Postgraduate 2 10%
Other 3 14%
Unknown 1 5%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 6 29%
Medicine and Dentistry 4 19%
Agricultural and Biological Sciences 3 14%
Pharmacology, Toxicology and Pharmaceutical Science 2 10%
Unspecified 1 5%
Other 2 10%
Unknown 3 14%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 October 2015.
All research outputs
#2,345,772
of 6,367,740 outputs
Outputs from Cell & Bioscience
#37
of 161 outputs
Outputs of similar age
#74,998
of 195,888 outputs
Outputs of similar age from Cell & Bioscience
#3
of 11 outputs
Altmetric has tracked 6,367,740 research outputs across all sources so far. This one has received more attention than most of these and is in the 61st percentile.
So far Altmetric has tracked 161 research outputs from this source. They receive a mean Attention Score of 2.0. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 195,888 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 59% of its contemporaries.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.