Title |
Why this is not multiple sclerosis: a case based approach
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Published in |
Arquivos de Neuro-Psiquiatria, October 2015
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DOI | 10.1590/0004-282x20150163 |
Pubmed ID | |
Authors |
Zaira Fernanda Martinho Nicolau, Enedina Maria Lobato de Oliveira, Denis Bernardi Bichuetti |
Abstract |
Objective To present a case series of patients previously diagnosed as multiple sclerosis (MS) which were later confirmed as an alternative diagnosis, and describe the clinical and paraclinical signs that led to this change.Method Nine patients are described. We reviewed the patient's clinical chart, magnetic resonance images (MRI) and cerebrospinal fluid.Results There was a mean of three typical symptoms of MS and four clinical red flags per patient. MRI red flags were found in 88,9% of all referrals, with a mean of 3 encountered per patient.Conclusion We identified that, not only the misdiagnosed patients did not fulfill MS diagnosis criteria, but also how the described red flags are a useful tool in the differentiation of MS from other diseases. This data is important for guiding future diagnosis, especially for general clinicians and neurologists, which directly interfere with the patient's management, treatment, prognosis and quality of life. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 33% |
Unknown | 2 | 67% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 25 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 6 | 24% |
Student > Postgraduate | 4 | 16% |
Student > Master | 3 | 12% |
Other | 2 | 8% |
Student > Ph. D. Student | 2 | 8% |
Other | 5 | 20% |
Unknown | 3 | 12% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 12 | 48% |
Nursing and Health Professions | 3 | 12% |
Neuroscience | 2 | 8% |
Psychology | 2 | 8% |
Economics, Econometrics and Finance | 1 | 4% |
Other | 1 | 4% |
Unknown | 4 | 16% |