The Paradoxical Role of NKG2D in Cancer Immunity https://t.co/7LYH2SH7ZL
3,585 followers
3,585 followers
https://t.co/ShQrzV15nK "In rheumatoid arthritis, the substantial amount of soluble MIC released by synoviocytes failed to downregulate NKG2D on CD4+ T cells, possibly due to high levels of IL-15 and TNF-α"
3,585 followers
https://t.co/ShQrzV15nK "This was shown in glioma patients with heterogeneous expression of NKG2D ligands where TGF-β selectively downregulated MICA and ULBP2 transcription, but not MICB, ULBP1, and ULBP3"
3,585 followers
https://t.co/ShQrzV15nK "TGF-β downregulates NKG2D on NK cells and CD8+ T cells in cancer patients and NKG2D ligands on cancer cells"