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Endothelial cell control of thrombosis

Overview of attention for article published in BMC Cardiovascular Disorders, October 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#35 of 1,040)
  • High Attention Score compared to outputs of the same age (90th percentile)
  • High Attention Score compared to outputs of the same age and source (96th percentile)

Mentioned by

twitter
19 tweeters
patent
1 patent
video
1 video uploader

Citations

dimensions_citation
162 Dimensions

Readers on

mendeley
330 Mendeley
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Title
Endothelial cell control of thrombosis
Published in
BMC Cardiovascular Disorders, October 2015
DOI 10.1186/s12872-015-0124-z
Pubmed ID
Authors

Jonathan W. Yau, Hwee Teoh, Subodh Verma

Abstract

Hemostasis encompasses a set of tightly regulated processes that govern blood clotting, platelet activation, and vascular repair. Upon vascular injury, the hemostatic system initiates a series of vascular events and activates extravascular receptors that act in concert to seal off the damage. Blood clotting is subsequently attenuated by a plethora of inhibitors that prevent excessive clot formation and eventual thrombosis. The endothelium which resides at the interface between the blood and surrounding tissues, serves an integral role in the hemostatic system. Depending on specific tissue needs and local stresses, endothelial cells are capable of evoking either antithrombotic or prothrombotic events. Healthy endothelial cells express antiplatelet and anticoagulant agents that prevent platelet aggregation and fibrin formation, respectively. In the face of endothelial dysfunction, endothelial cells trigger fibrin formation, as well as platelet adhesion and aggregation. Finally, endothelial cells release pro-fibrinolytic agents that initiate fibrinolysis to degrade the clot. Taken together, a functional endothelium is essential to maintain hemostasis and prevent thrombosis. Thus, a greater understanding into the role of the endothelium can provide new avenues for exploration and novel therapies for the management of thromboembolisms.

Twitter Demographics

The data shown below were collected from the profiles of 19 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 330 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
Spain 1 <1%
South Africa 1 <1%
Brazil 1 <1%
Unknown 326 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 67 20%
Student > Bachelor 48 15%
Student > Master 45 14%
Researcher 39 12%
Student > Postgraduate 23 7%
Other 60 18%
Unknown 48 15%
Readers by discipline Count As %
Medicine and Dentistry 84 25%
Biochemistry, Genetics and Molecular Biology 64 19%
Agricultural and Biological Sciences 34 10%
Engineering 22 7%
Pharmacology, Toxicology and Pharmaceutical Science 9 3%
Other 39 12%
Unknown 78 24%

Attention Score in Context

This research output has an Altmetric Attention Score of 18. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 September 2020.
All research outputs
#1,129,356
of 15,944,014 outputs
Outputs from BMC Cardiovascular Disorders
#35
of 1,040 outputs
Outputs of similar age
#26,365
of 286,636 outputs
Outputs of similar age from BMC Cardiovascular Disorders
#3
of 86 outputs
Altmetric has tracked 15,944,014 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,040 research outputs from this source. They receive a mean Attention Score of 3.7. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 286,636 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 86 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.