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Neuro-developmental outcome of a large cohort of growth discordant twins

Overview of attention for article published in European Journal of Pediatrics, October 2015
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (55th percentile)
  • Good Attention Score compared to outputs of the same age and source (65th percentile)

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4 tweeters

Citations

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15 Dimensions

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52 Mendeley
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Title
Neuro-developmental outcome of a large cohort of growth discordant twins
Published in
European Journal of Pediatrics, October 2015
DOI 10.1007/s00431-015-2648-8
Pubmed ID
Authors

Cecilie Halling, Fergal D. Malone, Fionnuala M. Breathnach, Moira C. Stewart, Fionnuala M. McAuliffe, John J. Morrison, Patrick Dicker, Fiona Manning, John David Corcoran

Abstract

Our aims were to study the effect of birthweight growth discordance (≥20 %) on neuro-developmental outcome of monochorionic and dichorionic twins and to compare the relative effects of foetal growth discordance and prematurity on cognitive outcome. We performed a cross-sectional multicentre prospective follow-up study from a cohort of 948 twin pregnancies. One hundred nineteen birthweight-discordant twin pairs were examined (24 monochorionic pairs) and were matched for gestational age at delivery with 111 concordant control pairs. Participants were assessed with the Bayley Scales between 24 and 42 months of age. Analysis was by paired t test for intra-twin pair differences and by multiple linear regression. Compared to the larger twin of a discordant pair, the smaller twin performed significantly worse in cognition (mean composite cognitive score difference = -1.7, 95 % confidence interval (CI) = 0.3-3.1, p = 0.01) and also in language and motor skills. Prematurity prior to 33 weeks' gestation, however, had a far greater impact on cognitive outcomes (mean cognitive composite score difference = -5.8, 95 % CI = 1.2-10.5, p = 0.008). Birthweight growth discordance of ≥20 % confers an independent adverse effect on long-term neuro-development of the smaller twin. However, prior to 33 weeks' gestation, gestational age at birth adversely affects cognitive development to a greater extent than foetal growth discordance. What is known: • Growth discordance is a common problem encountered in monochorionic and dichorionic twin pregnancies. • Previous studies have demonstrated adverse developmental outcomes in one or two areas of development. What is new: • Growth discordance has a negative impact on all three areas of development: cognition, language and motor skills. • The current study is amongst the first to compare the impact of growth discordance and prematurity on cognitive outcomes.

Twitter Demographics

The data shown below were collected from the profiles of 4 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 52 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 9 17%
Researcher 8 15%
Student > Ph. D. Student 6 12%
Student > Bachelor 5 10%
Student > Doctoral Student 5 10%
Other 11 21%
Unknown 8 15%
Readers by discipline Count As %
Medicine and Dentistry 19 37%
Psychology 9 17%
Nursing and Health Professions 4 8%
Sports and Recreations 3 6%
Agricultural and Biological Sciences 2 4%
Other 5 10%
Unknown 10 19%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 February 2016.
All research outputs
#6,869,730
of 12,220,965 outputs
Outputs from European Journal of Pediatrics
#1,287
of 2,136 outputs
Outputs of similar age
#108,213
of 254,546 outputs
Outputs of similar age from European Journal of Pediatrics
#23
of 72 outputs
Altmetric has tracked 12,220,965 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,136 research outputs from this source. They receive a mean Attention Score of 3.9. This one is in the 37th percentile – i.e., 37% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 254,546 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 55% of its contemporaries.
We're also able to compare this research output to 72 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.