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Rifampin resistance and diabetes mellitus in a cross-sectional study of adult patients in rural South India

Overview of attention for article published in BMC Infectious Diseases, October 2015
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Title
Rifampin resistance and diabetes mellitus in a cross-sectional study of adult patients in rural South India
Published in
BMC Infectious Diseases, October 2015
DOI 10.1186/s12879-015-1204-5
Pubmed ID
Authors

Saurabh Mehta, Elaine Ann Yu, Syed Fazil Ahamed, Wesley Bonam, John Kenneth

Abstract

Despite increasing reports of the linkage between diabetes and tuberculosis (TB), there is limited information regarding diabetes and TB drug resistance. In this cross-sectional study, sputum and blood samples were collected from 304 adult patients in rural Andhra Pradesh. Rifampin resistance was assessed by Xpert MTB/RIF (Xpert), and diabetes status was based on self-report. Additionally, samples were assayed by acid-fast bacilli sputum smear microscopy (AFB) and QuantiFERON-TB Gold In-Tube (QFT-G), in order to compare relative diagnostic performances. Among patients with confirmed TB (n = 194), diabetes was associated with 3.0-fold higher risk of rifampin resistance (95 % CI 1.3-6.7). Considering Xpert MTB/RIF the gold standard, AFB had lower sensitivity (72.2 vs. 82.5 %) and higher specificity (96.4 vs. 37.0 %) compared to QFT-G for diagnosing TB. The increased risk of rifampin resistance in patients with diabetes highlights the need for integrated diabetes surveillance in TB programs, particularly in settings undergoing the epidemiological transition.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 89 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 1 1%
Unknown 88 99%

Demographic breakdown

Readers by professional status Count As %
Student > Master 16 18%
Student > Bachelor 10 11%
Researcher 9 10%
Student > Ph. D. Student 8 9%
Student > Postgraduate 7 8%
Other 17 19%
Unknown 22 25%
Readers by discipline Count As %
Medicine and Dentistry 32 36%
Nursing and Health Professions 11 12%
Immunology and Microbiology 5 6%
Agricultural and Biological Sciences 2 2%
Biochemistry, Genetics and Molecular Biology 2 2%
Other 8 9%
Unknown 29 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 May 2016.
All research outputs
#18,429,829
of 22,831,537 outputs
Outputs from BMC Infectious Diseases
#5,602
of 7,678 outputs
Outputs of similar age
#204,669
of 284,375 outputs
Outputs of similar age from BMC Infectious Diseases
#130
of 166 outputs
Altmetric has tracked 22,831,537 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,678 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.6. This one is in the 15th percentile – i.e., 15% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 284,375 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 166 others from the same source and published within six weeks on either side of this one. This one is in the 3rd percentile – i.e., 3% of its contemporaries scored the same or lower than it.