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The frequency of oral conditions detected in hematology inpatients

Overview of attention for article published in Hematology Transfusion and Cell Therapy, April 2018
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The frequency of oral conditions detected in hematology inpatients
Published in
Hematology Transfusion and Cell Therapy, April 2018
DOI 10.1016/j.htct.2018.02.006
Pubmed ID

Alessandra Oliveira Ferrari Gomes, Arley Silva, Cesar Werneck Noce, Marisa Ferreira, Angelo Maiolino, Sandra Regina Torres


Oral manifestations may be the first signs of hematologic diseases, and may occur due to the disease itself or to treatment. To evaluate the frequency and types of oral conditions presented by patients on a hematology ward. Data were collected by oral examinations during weekly visits to a hematology ward. Six trained dentists performed the oral assessment based on the principles of oral semiology. All patients who accepted to be examined were included in the study. Patients who were unavailable or unable to have oral examinations were excluded. Data were recorded on protocol forms and in the electronic records of the institution. A descriptive analysis was performed. Seventy-nine patients were included in the analysis; 50.6% were female and the mean age was 41.49 years. The most common reasons for hospitalization were chemotherapy and complications (81%), relapse (13.9%) and pre-transplant preparation (5%). The most frequent underlying diseases were multiple myeloma (17.7%), acute myeloid leukemia (15.4%) and acute lymphocytic leukemia (11.5%). Oral conditions were found in 36 (45.6%) patients, some of whom presented more than one condition. The most common oral conditions were dry lips (12.6%), mucositis (10.1%), petechiae (8.9%) and candidiasis (7.6%). Of the detected oral conditions, 56.9% were related to the underlying disease or chemotherapy and 20.2% were not related to the disease. This study shows the types and frequency of oral conditions observed in hematological inpatients. Awareness of these conditions is important for prevention and planning the care of patients with hematological diseases.

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Geographical breakdown

Country Count As %
Unknown 61 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 8 13%
Student > Postgraduate 7 11%
Student > Doctoral Student 6 10%
Student > Master 6 10%
Student > Ph. D. Student 3 5%
Other 7 11%
Unknown 24 39%
Readers by discipline Count As %
Medicine and Dentistry 26 43%
Biochemistry, Genetics and Molecular Biology 1 2%
Nursing and Health Professions 1 2%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Immunology and Microbiology 1 2%
Other 3 5%
Unknown 28 46%