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X Demographics
Mendeley readers
| Title |
Ventricular tachycardia in ischemic cardiomyopathy; a combined endo-epicardial ablation as the first procedure versus a stepwise approach (EPILOGUE) – study protocol for a randomized controlled trial
|
|---|---|
| Published in |
Trials, October 2015
|
| DOI | 10.1186/s13063-015-1005-6 |
| Pubmed ID | |
| Authors |
Astrid A. Hendriks, Muchtiar Khan, Laszlo Geller, Attila Kardos, Lennart J. de Vries, Sing-Chien Yap, Sip A. Wijchers, Dominic AMJ Theuns, Tamas Szili-Torok |
| Abstract |
The role of epicardial substrate ablation of ventricular tachycardia (VT) as a first-line approach in patients with ischemic heart disease is not clearly defined. Epicardial ablation as a first-line option is standard for patients with nonischemic dilated cardiomyopathy and arrhythmogenic right ventricular cardiomyopathy. Several nonrandomized studies, including studies on patients with ischemic heart disease, have shown that epicardial VT ablation improves outcome but this approach was often used after a failed endocardial approach. The aim of this study is to determine whether a combined endo-epicardial scar homogenization as a first-line approach will improve the outcome of VT ablation. The EPILOGUE study is a multicenter, two-armed, nonblinded, randomized controlled trial. Patients with ischemic heart disease who are referred for VT ablation will be randomly assigned to combined endo-epicardial scar homogenization or endocardial scar homogenization only (control group). The primary outcome is recurrence of sustained VT during a 2-year follow-up. Secondary outcomes include procedural success and safety. This study is the first randomized trial that evaluates the role of a combined endo-epicardial scar homogenization versus endocardial scar homogenization for the treatment of ischemic scar-related VT. NL4816807814v02. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 43 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 43 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 8 | 19% |
| Researcher | 7 | 16% |
| Professor | 4 | 9% |
| Professor > Associate Professor | 4 | 9% |
| Student > Postgraduate | 3 | 7% |
| Other | 8 | 19% |
| Unknown | 9 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 25 | 58% |
| Economics, Econometrics and Finance | 2 | 5% |
| Unspecified | 1 | 2% |
| Biochemistry, Genetics and Molecular Biology | 1 | 2% |
| Sports and Recreations | 1 | 2% |
| Other | 1 | 2% |
| Unknown | 12 | 28% |