↓ Skip to main content

Aerobic bacterial profile and antibiotic resistance in patients with diabetic foot infections

Overview of attention for article published in Revista da Sociedade Brasileira de Medicina Tropical, October 2015
Altmetric Badge

Mentioned by

twitter
2 tweeters

Citations

dimensions_citation
44 Dimensions

Readers on

mendeley
126 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Aerobic bacterial profile and antibiotic resistance in patients with diabetic foot infections
Published in
Revista da Sociedade Brasileira de Medicina Tropical, October 2015
DOI 10.1590/0037-8682-0146-2015
Pubmed ID
Authors

Michele Cezimbra Perim, Joelma da Costa Borges, Stela Regina Costa Celeste, Ederson de Freitas Orsolin, Rafael Rocha Mendes, Gabriella Oliveira Mendes, Roumayne Lopes Ferreira, Solange Cristina Carreiro, Maria Cristina da Silva Pranchevicius

Abstract

This study aimed to determine the frequencies of bacterial isolates cultured from diabetic foot infections and assess their resistance and susceptibility to commonly used antibiotics. This prospective study included 41 patients with diabetic foot lesions. Bacteria were isolated from foot lesions, and their antibiotic susceptibility pattern was determined using the Kirby-Bauer disk diffusion method and/or broth method [minimum inhibitory concentration (MIC)]. The most common location of ulceration was the toe (54%), followed by the plantar surface (27%) and dorsal portion (19%). A total of 89 bacterial isolates were obtained from 30 patients. The infections were predominantly due to Gram-positive bacteria and polymicrobial bacteremia. The most commonly isolated Gram-positive bacteria were Staphylococcus aureus, followed by Staphylococcus saprophyticus, Staphylococcus epidermidis, Streptococcus agalactiae, and Streptococcus pneumoniae. The most commonly isolated Gram-negative bacteria were Proteus spp. and Enterobacterspp., followed by Escherichia coli, Pseudomonasspp., and Citrobacterspp. Nine cases of methicillin-resistant Staphylococcus aureus (MRSA) had cefoxitin resistance, and among these MRSA isolates, 3 were resistant to vancomycin with the MIC technique. The antibiotic imipenem was the most effective against both Gram-positive and Gram-negative bacteria, and gentamicin was effective against Gram-negative bacteria. The present study confirmed the high prevalence of multidrug-resistant pathogens in diabetic foot ulcers. It is necessary to evaluate the different microorganisms infecting the wound and to know the antibiotic susceptibility patterns of the isolates from the infected wound. This knowledge is crucial for planning treatment with the appropriate antibiotics, reducing resistance patterns, and minimizing healthcare costs.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 126 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Italy 1 <1%
Unknown 125 99%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 23 18%
Student > Master 20 16%
Student > Ph. D. Student 13 10%
Student > Postgraduate 10 8%
Researcher 9 7%
Other 21 17%
Unknown 30 24%
Readers by discipline Count As %
Medicine and Dentistry 29 23%
Immunology and Microbiology 24 19%
Biochemistry, Genetics and Molecular Biology 9 7%
Pharmacology, Toxicology and Pharmaceutical Science 8 6%
Nursing and Health Professions 7 6%
Other 15 12%
Unknown 34 27%