Title |
Detection of Leishmania (Viannia) DNA in leucocytes from the blood of patients with cutaneous leishmaniasis
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Published in |
Revista da Sociedade Brasileira de Medicina Tropical, October 2015
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DOI | 10.1590/0037-8682-0052-2015 |
Pubmed ID | |
Authors |
Carolina Cella Conter, Herintha Coeto Neitzke-Abreu, Raissa Bocchi Pedroso, Maria Valdrinez Campana Lonardoni, Thaís Gomes Verzignassi Silveira, Sandra Mara Alessi Aristides |
Abstract |
Cutaneous leishmaniasis (CL) is a serious and global public health issue, with the potential of developing a mucosal form, occurring as subclinical cases, and showing recurrence despite previous treatment. Polymorphonuclear and mononuclear DNA obtained from 49 patients was subjected to polymerase chain reaction for detection of Leishmania (Viannia). DNA was detected in mononuclear cells from two patients with active primary lesions positive for CL, with infection periods of 3 and 6 months, respectively. The DNA of Leishmania (Viannia) indicates probable parasite dissemination possibly explaining subclinical case emergence, lesion recurrence, and mucosal lesion appearance. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Brazil | 1 | 4% |
Unknown | 27 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Professor > Associate Professor | 5 | 18% |
Student > Bachelor | 4 | 14% |
Student > Master | 4 | 14% |
Researcher | 4 | 14% |
Student > Doctoral Student | 3 | 11% |
Other | 3 | 11% |
Unknown | 5 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Immunology and Microbiology | 7 | 25% |
Veterinary Science and Veterinary Medicine | 3 | 11% |
Medicine and Dentistry | 3 | 11% |
Biochemistry, Genetics and Molecular Biology | 2 | 7% |
Psychology | 2 | 7% |
Other | 5 | 18% |
Unknown | 6 | 21% |