Title |
Percutaneous Coronary Intervention in Familial Hypercholesterolemia Is Understudied
|
---|---|
Published in |
Frontiers in Cardiovascular Medicine, August 2018
|
DOI | 10.3389/fcvm.2018.00116 |
Pubmed ID | |
Authors |
Leo Ungar, David Sanders, Brian Becerra, Ailin Barseghian |
Abstract |
Familial hypercholesterolemia (FH) is a common heritable condition in which mutations of genes governing cholesterol metabolism result in elevated LDL levels and accelerated atherosclerosis. The treatment of FH focuses on lipid lowering drugs to decrease patients' cholesterol levels and reduce their risk of cardiovascular events. Even with optimal medical therapy, some FH patients will develop coronary atherosclerosis, suffer myocardial infarction, and require revascularization. Yet, the revascularization of FH patients has not been widely studied. Here we review FH, identify unanswered questions in the interventional management of FH patients, and explore barriers and opportunities for answering these questions. Further research is needed in this neglected but important topic in interventional cardiology. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Poland | 2 | 40% |
Australia | 1 | 20% |
United States | 1 | 20% |
Switzerland | 1 | 20% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 60% |
Scientists | 1 | 20% |
Practitioners (doctors, other healthcare professionals) | 1 | 20% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 18 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 7 | 39% |
Student > Postgraduate | 2 | 11% |
Researcher | 2 | 11% |
Professor | 1 | 6% |
Student > Doctoral Student | 1 | 6% |
Other | 1 | 6% |
Unknown | 4 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 9 | 50% |
Biochemistry, Genetics and Molecular Biology | 2 | 11% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 6% |
Unknown | 6 | 33% |