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Sequence similarity between the erythrocyte binding domain of the Plasmodium vivax Duffy binding protein and the V3 loop of HIV-1 strain MN reveals a functional heparin binding motif involved in…

Overview of attention for article published in Virology Journal, November 2011
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Title
Sequence similarity between the erythrocyte binding domain of the Plasmodium vivax Duffy binding protein and the V3 loop of HIV-1 strain MN reveals a functional heparin binding motif involved in binding to the Duffy antigen receptor for chemokines
Published in
Virology Journal, November 2011
DOI 10.1186/1743-422x-8-523
Pubmed ID
Authors

Michael J Bolton, Robert F Garry

Abstract

The HIV surface glycoprotein gp120 (SU, gp120) and the Plasmodium vivax Duffy binding protein (PvDBP) bind to chemokine receptors during infection and have a site of amino acid sequence similarity in their binding domains that often includes a heparin binding motif (HBM). Infection by either pathogen has been found to be inhibited by polyanions.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 46 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
India 1 2%
South Africa 1 2%
Brazil 1 2%
Unknown 42 91%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 17%
Student > Ph. D. Student 6 13%
Student > Master 3 7%
Student > Doctoral Student 2 4%
Student > Bachelor 2 4%
Other 6 13%
Unknown 19 41%
Readers by discipline Count As %
Agricultural and Biological Sciences 15 33%
Medicine and Dentistry 4 9%
Biochemistry, Genetics and Molecular Biology 3 7%
Arts and Humanities 1 2%
Unspecified 1 2%
Other 2 4%
Unknown 20 43%