↓ Skip to main content

Quantitative analysis of iris parameters in keratoconus patients using optical coherence tomography

Overview of attention for article published in Arquivos Brasileiros de Oftalmologia, January 2015
Altmetric Badge

Mentioned by

twitter
1 X user

Citations

dimensions_citation
6 Dimensions

Readers on

mendeley
20 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Quantitative analysis of iris parameters in keratoconus patients using optical coherence tomography
Published in
Arquivos Brasileiros de Oftalmologia, January 2015
DOI 10.5935/0004-2749.20150080
Pubmed ID
Authors

Gustavo Bonfadini, Karun Arora, Lucas M. Vianna, Mauro Campos, David Friedman, Beatriz Muñoz, Albert S. Jun

Abstract

To investigate the relationship between quantitative iris parameters and the presence of keratoconus. Cross-sectional observational study that included 15 affected eyes of 15 patients with keratoconus and 26 eyes of 26 normal age- and sex-matched controls. Iris parameters (area, thickness, and pupil diameter) of affected and unaffected eyes were measured under standardized light and dark conditions using anterior segment optical coherence tomography (AS-OCT). To identify optimal iris thickness cutoff points to maximize the sensitivity and specificity when discriminating keratoconus eyes from normal eyes, the analysis included the use of receiver operating characteristic (ROC) curves. Iris thickness and area were lower in keratoconus eyes than in normal eyes. The mean thickness at the pupillary margin under both light and dark conditions was found to be the best parameter for discriminating normal patients from keratoconus patients. Diagnostic performance was assessed by the area under the ROC curve (AROC), which had a value of 0.8256 with 80.0% sensitivity and 84.6% specificity, using a cutoff of 0.4125 mm. The sensitivity increased to 86.7% when a cutoff of 0.4700 mm was used. In our sample, iris thickness was lower in keratoconus eyes than in normal eyes. These results suggest that tomographic parameters may provide novel adjunct approaches for keratoconus screening.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 20 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 20 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 4 20%
Student > Ph. D. Student 3 15%
Other 2 10%
Student > Bachelor 1 5%
Student > Doctoral Student 1 5%
Other 1 5%
Unknown 8 40%
Readers by discipline Count As %
Medicine and Dentistry 6 30%
Biochemistry, Genetics and Molecular Biology 1 5%
Business, Management and Accounting 1 5%
Computer Science 1 5%
Pharmacology, Toxicology and Pharmaceutical Science 1 5%
Other 4 20%
Unknown 6 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 November 2015.
All research outputs
#22,759,452
of 25,373,627 outputs
Outputs from Arquivos Brasileiros de Oftalmologia
#322
of 446 outputs
Outputs of similar age
#306,533
of 359,528 outputs
Outputs of similar age from Arquivos Brasileiros de Oftalmologia
#28
of 52 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 446 research outputs from this source. They receive a mean Attention Score of 2.5. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 359,528 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 52 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.