Title |
Growth Hormone Deficiency Is Frequent After Recent Stroke
|
---|---|
Published in |
Frontiers in Neurology, September 2018
|
DOI | 10.3389/fneur.2018.00713 |
Pubmed ID | |
Authors |
Thomas Lillicrap, Carlos Garcia-Esperon, Frederick Rohan Walker, Lin Kooi Ong, Michael Nilsson, Neil Spratt, Christopher R. Levi, Mark Parsons, Jörgen Isgaard, Andrew Bivard |
Abstract |
Introduction: The incidence of pituitary dysfunction after severe ischemic stroke is unknown, however given the increasing attention to pituitary dysfunction after neurological injuries such as traumatic brain injury, this may represent a novel area of research in stroke. Methods: We perform an arginine and human growth hormone releasing hormone challenge on ischemic stroke patients within a week of symptom onset. Results: Over the study period, 13 patients were successfully tested within a week of stroke (baseline NIHSS 10, range 7-16). Overall, 9(69%) patients had a poor response, with 7(54%) of these patients meeting the criteria for had human growth hormone deficiency. Other measures of pituitary function were within normal ranges. Conclusion: After major ischemic stroke, low GH levels are common and may play a role in stroke recovery. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Australia | 3 | 38% |
United Kingdom | 1 | 13% |
Unknown | 4 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 4 | 50% |
Scientists | 3 | 38% |
Practitioners (doctors, other healthcare professionals) | 1 | 13% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 18 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 3 | 17% |
Student > Bachelor | 3 | 17% |
Student > Ph. D. Student | 2 | 11% |
Student > Master | 2 | 11% |
Other | 1 | 6% |
Other | 1 | 6% |
Unknown | 6 | 33% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 6 | 33% |
Neuroscience | 4 | 22% |
Biochemistry, Genetics and Molecular Biology | 1 | 6% |
Sports and Recreations | 1 | 6% |
Unknown | 6 | 33% |