Evidence and consensus based guideline for the management of delirium, analgesia, and sedation in intensive care medicine. Revision 2015 (DAS-Guideline 2015) – short version

Evidence and consensus based guideline for the management of delirium, analgesia, and sedation in intensive care medicine. Revision 2015 (DAS-Guideline 2015) – short version

GMS German Medical Science, November 2015

26609286

DAS-Taskforce 2015, Ralf Baron, Andreas Binder, Rolf Biniek, Stephan Braune, Hartmut Buerkle, Peter Dall, Sueha Demirakca, Rahel Eckardt, Verena Eggers, Ingolf Eichler, Ingo Fietze, Stephan Freys, Andreas Fründ, Lars Garten, Bernhard Gohrbandt, Irene Harth, Wolfgang Hartl, Hans-Jürgen Heppner, Johannes Horter, Ralf Huth, Uwe Janssens, Christine Jungk, Kristin Maria Kaeuper, Paul Kessler, Stefan Kleinschmidt, Matthias Kochanek, Matthias Kumpf, Andreas Meiser, Anika Mueller, Maritta Orth, Christian Putensen, Bernd Roth, Michael Schaefer, Rainhild Schaefers, Peter Schellongowski, Monika Schindler, Reinhard Schmitt, Jens Scholz, Stefan Schroeder, Gerhard Schwarzmann, Claudia Spies, Robert Stingele, Peter Tonner, Uwe Trieschmann, Michael Tryba, Frank Wappler, Christian Waydhas, Bjoern Weiss, Guido Weisshaar

In 2010, under the guidance of the DGAI (German Society of Anaesthesiology and Intensive Care Medicine) and DIVI (German Interdisciplinary Association for Intensive Care and Emergency Medicine), twelve German medical societies published the "Evidence- and Consensus-based Guidelines on the Management of Analgesia, Sedation and Delirium in Intensive Care". Since then, several new studies and publications have considerably increased the body of evidence, including the new recommendations from the American College of Critical Care Medicine (ACCM) in conjunction with Society of Critical Care Medicine (SCCM) and American Society of Health-System Pharmacists (ASHP) from 2013. For this update, a major restructuring and extension of the guidelines were needed in order to cover new aspects of treatment, such as sleep and anxiety management. The literature was systematically searched and evaluated using the criteria of the Oxford Center of Evidence Based Medicine. The body of evidence used to formulate these recommendations was reviewed and approved by representatives of 17 national societies. Three grades of recommendation were used as follows: Grade "A" (strong recommendation), Grade "B" (recommendation) and Grade "0" (open recommendation). The result is a comprehensive, interdisciplinary, evidence and consensus-based set of level 3 guidelines. This publication was designed for all ICU professionals, and takes into account all critically ill patient populations. It represents a guide to symptom-oriented prevention, diagnosis, and treatment of delirium, anxiety, stress, and protocol-based analgesia, sedation, and sleep-management in intensive care medicine.