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Echocardiographic Predictors of Worse Outcome After Cardiac Resynchronization Therapy

Overview of attention for article published in Arquivos Brasileiros de Cardiologia, January 2015
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Title
Echocardiographic Predictors of Worse Outcome After Cardiac Resynchronization Therapy
Published in
Arquivos Brasileiros de Cardiologia, January 2015
DOI 10.5935/abc.20150108
Pubmed ID
Authors

Eduardo Arrais Rocha, Francisca Tatiana Moreira Pereira, José Sebastião Abreu, José Wellington O. Lima, Marcelo de Paula M. Monteiro, Almino Cavalcante Rocha Neto, Ana Rosa Pinto Quidute, Camilla Viana A. Goés, Carlos Roberto Martins Rodrigues Sobrinho, Maurício Ibrahim Scanavacca

Abstract

Cardiac resynchronization therapy (CRT) is the recommended treatment by leading global guidelines. However, 30%-40% of selected patients are non-responders. To develop an echocardiographic model to predict cardiac death or transplantation (Tx) 1 year after CRT. Observational, prospective study, with the inclusion of 116 patients, aged 64.89 ± 11.18 years, 69.8% male, 68,1% in NYHA FC III and 31,9% in FC IV, 71.55% with left bundle-branch block, and median ejection fraction (EF) of 29%. Evaluations were made in the pre‑implantation period and 6-12 months after that, and correlated with cardiac mortality/Tx at the end of follow-up. Cox and logistic regression analyses were performed with ROC and Kaplan-Meier curves. The model was internally validated by bootstrapping. There were 29 (25%) deaths/Tx during follow-up of 34.09 ± 17.9 months. Cardiac mortality/Tx was 16.3%. In the multivariate Cox model, EF < 30%, grade III/IV diastolic dysfunction and grade III mitral regurgitation at 6‑12 months were independently related to increased cardiac mortality or Tx, with hazard ratios of 3.1, 4.63 and 7.11, respectively. The area under the ROC curve was 0.78. EF lower than 30%, severe diastolic dysfunction and severe mitral regurgitation indicate poor prognosis 1 year after CRT. The combination of two of those variables indicate the need for other treatment options.

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Mendeley readers

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Geographical breakdown

Country Count As %
Unknown 22 100%

Demographic breakdown

Readers by professional status Count As %
Unknown 22 100%
Readers by discipline Count As %
Unknown 22 100%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 December 2015.
All research outputs
#8,573,347
of 13,643,660 outputs
Outputs from Arquivos Brasileiros de Cardiologia
#200
of 513 outputs
Outputs of similar age
#186,292
of 356,829 outputs
Outputs of similar age from Arquivos Brasileiros de Cardiologia
#11
of 23 outputs
Altmetric has tracked 13,643,660 research outputs across all sources so far. This one is in the 23rd percentile – i.e., 23% of other outputs scored the same or lower than it.
So far Altmetric has tracked 513 research outputs from this source. They receive a mean Attention Score of 2.0. This one is in the 49th percentile – i.e., 49% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 356,829 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.