| Chapter title |
Epigenetic Regulation of Human Neural Stem Cell Differentiation
|
|---|---|
| Chapter number | 5 |
| Book title |
Human Neural Stem Cells
|
| Published in |
Results and problems in cell differentiation, January 2018
|
| DOI | 10.1007/978-3-319-93485-3_5 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-993484-6, 978-3-31-993485-3
|
| Authors |
Mizuki Honda, Kinichi Nakashima, Sayako Katada, Honda, Mizuki, Nakashima, Kinichi, Katada, Sayako |
| Abstract |
Emerging evidence has demonstrated that epigenetic programs influence many aspects of neural stem cell (NSC) behavior, including proliferation and differentiation. It is becoming apparent that epigenetic mechanisms, such as DNA methylation, histone modifications, and noncoding RNA expression, are spatiotemporally regulated and that these intracellular programs, in concert with extracellular signals, ensure appropriate gene activation. Here we summarize recent advances in understanding of the epigenetic regulation of human NSCs directly isolated from the brain or produced from pluripotent stem cells (embryonic and induced pluripotent stem cells, respectively). |
X Demographics
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|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 7 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 3 | 43% |
| Student > Master | 2 | 29% |
| Student > Ph. D. Student | 1 | 14% |
| Unknown | 1 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 2 | 29% |
| Agricultural and Biological Sciences | 1 | 14% |
| Psychology | 1 | 14% |
| Neuroscience | 1 | 14% |
| Unknown | 2 | 29% |