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Development of Antibody-Based Therapeutics

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Cover of 'Development of Antibody-Based Therapeutics'

Table of Contents

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    Book Overview
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    Chapter 1 Introduction
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    Chapter 2 Translational Considerations and Challenges: An Overview
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    Chapter 3 Considerations for Construct and Affinity Design Goals
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    Chapter 4 Epitope Characterization and Isotype Selection
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    Chapter 5 Biophysical Considerations for Development of Antibody-Based Therapeutics
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    Chapter 6 Novel Technologies for Generation of Bispecific Constructs
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    Chapter 7 Stimulus-Response Mechanisms: An Overview
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    Chapter 8 Evaluation of Tumor Growth Inhibition in Preclinical Tumor Models: A Quantitative Approach
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    Chapter 9 Application of Proof-of-Mechanism Biomarkers (POM) in Design and Development of Biologics Modalities
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    Chapter 10 Antibody Drug Conjugates: Translational Considerations
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    Chapter 11 Application of PK-PD Modeling and Simulation Approaches for Immuno-Oncology Drugs
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    Chapter 12 Translational Biomarkers: Application in the Clinical Development of Combination Therapies
Attention for Chapter 2: Translational Considerations and Challenges: An Overview
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