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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Central nervous system myeloid cells as drug targets: current status and translational challenges
|
|---|---|
| Published in |
Nature Reviews Drug Discovery, December 2015
|
| DOI | 10.1038/nrd.2015.14 |
| Pubmed ID | |
| Authors |
Knut Biber, Thomas Möller, Erik Boddeke, Marco Prinz |
| Abstract |
Myeloid cells of the central nervous system (CNS), which include parenchymal microglia, macrophages at CNS interfaces and monocytes recruited from the circulation during disease, are increasingly being recognized as targets for therapeutic intervention in neurological and psychiatric diseases. The origin of these cells in the immune system distinguishes them from ectodermal neurons and other glia and endows them with potential drug targets distinct from classical CNS target groups. However, despite the identification of several promising therapeutic approaches and molecular targets, no agents directly targeting these cells are currently available. Here, we assess strategies for targeting CNS myeloid cells and address key issues associated with their translation into the clinic. |
X Demographics
The data shown below were collected from the profiles of 21 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 6 | 29% |
| United Kingdom | 2 | 10% |
| Spain | 1 | 5% |
| Venezuela, Bolivarian Republic of | 1 | 5% |
| Ecuador | 1 | 5% |
| Russia | 1 | 5% |
| Unknown | 9 | 43% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 15 | 71% |
| Scientists | 4 | 19% |
| Science communicators (journalists, bloggers, editors) | 1 | 5% |
| Practitioners (doctors, other healthcare professionals) | 1 | 5% |
Mendeley readers
The data shown below were compiled from readership statistics for 207 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 3 | 1% |
| United Kingdom | 1 | <1% |
| Switzerland | 1 | <1% |
| Saudi Arabia | 1 | <1% |
| Unknown | 201 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 47 | 23% |
| Researcher | 43 | 21% |
| Student > Master | 23 | 11% |
| Student > Bachelor | 19 | 9% |
| Professor | 14 | 7% |
| Other | 29 | 14% |
| Unknown | 32 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 52 | 25% |
| Agricultural and Biological Sciences | 42 | 20% |
| Medicine and Dentistry | 28 | 14% |
| Biochemistry, Genetics and Molecular Biology | 19 | 9% |
| Pharmacology, Toxicology and Pharmaceutical Science | 9 | 4% |
| Other | 17 | 8% |
| Unknown | 40 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 19. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 November 2023.
All research outputs
#2,017,499
of 25,866,425 outputs
Outputs from Nature Reviews Drug Discovery
#968
of 3,697 outputs
Outputs of similar age
#32,335
of 396,781 outputs
Outputs of similar age from Nature Reviews Drug Discovery
#15
of 58 outputs
Altmetric has tracked 25,866,425 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,697 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 30.2. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 396,781 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 58 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.